diff --git a/build/TrimmingEnable.props b/build/TrimmingEnable.props
index 3e22699d3f..6bb5579b24 100644
--- a/build/TrimmingEnable.props
+++ b/build/TrimmingEnable.props
@@ -8,7 +8,7 @@
   </PropertyGroup>
 
   <PropertyGroup Condition="$([MSBuild]::IsTargetFrameworkCompatible('$(TargetFramework)', 'net8.0'))">
-    <IsAotCompatible>true</IsAotCompatible>
+    <IsAotCompatible Condition="'$(IsAotCompatible)' == ''">true</IsAotCompatible>
   </PropertyGroup>
 
   <!-- Remove check for the AOT when we get rid of dependencies with reflection -->
@@ -17,7 +17,7 @@
     <!-- Trim warnings -->
     <WarningsAsErrors>$(WarningsAsErrors);IL2000;IL2001;IL2002;IL2003;IL2004;IL2005;IL2006;IL2007;IL2008;IL2009;IL2010;IL2011;IL2012;IL2013;IL2014;IL2015;IL2016;IL2017;IL2018;IL2019;IL2020;IL2021;IL2022;IL2023;IL2024;IL2025;IL2026;IL2027;IL2028;IL2029;IL2030;IL2031;IL2032;IL2033;IL2034;IL2035;IL2036;IL2037;IL2038;IL2039;IL2040;IL2041;IL2042;IL2043;IL2044;IL2045;IL2046;IL2047;IL2048;IL2049;IL2050;IL2051;IL2052;IL2053;IL2054;IL2055;IL2056;IL2057;IL2058;IL2059;IL2060;IL2061;IL2062;IL2063;IL2064;IL2065;IL2066;IL2067;IL2068;IL2069;IL2070;IL2071;IL2072;IL2073;IL2074;IL2075;IL2076;IL2077;IL2078;IL2079;IL2080;IL2081;IL2082;IL2083;IL2084;IL2085;IL2086;IL2087;IL2088;IL2089;IL2090;IL2091;IL2092;IL2093;IL2094;IL2095;IL2096;IL2097;IL2098;IL2099;IL2100;IL2101;IL2102;IL2103;IL2104;IL2105;IL2106;IL2107;IL2108;IL2109;IL2110;IL2111;IL2112;IL2113;IL2114;IL2115;IL2116;IL2117;IL2118;IL2119;IL2120;IL2121;IL2122;IL2123;IL2124;IL2125;IL2126;IL2127;IL2128;IL2129;IL2130;IL2131;IL2132;IL2133;IL2134;IL2135;IL2136;IL2137;IL2138;IL2139;IL2140;IL2141;IL2142;IL2143;IL2144;IL2145;IL2146;IL2147;IL2148;IL2149;IL2150;IL2151;IL2152;IL2153;IL2154;IL2155;IL2156;IL2157</WarningsAsErrors>
     <!-- NativeAOT warnings -->
-    <WarningsAsErrors>$(WarningsAsErrors);IL3050;IL3051;IL3052;IL3053;IL3054;IL3055;IL3056</WarningsAsErrors>
+    <WarningsAsErrors Condition="'$(IsAotCompatible)' == 'true'">$(WarningsAsErrors);IL3050;IL3051;IL3052;IL3053;IL3054;IL3055;IL3056</WarningsAsErrors>
   </PropertyGroup>
 
 </Project>
diff --git a/src/Avalonia.Controls.ColorPicker/Helpers/ColorHelper.cs b/src/Avalonia.Controls.ColorPicker/Helpers/ColorHelper.cs
index c9801c432b..7d03c1bfd0 100644
--- a/src/Avalonia.Controls.ColorPicker/Helpers/ColorHelper.cs
+++ b/src/Avalonia.Controls.ColorPicker/Helpers/ColorHelper.cs
@@ -15,7 +15,12 @@ namespace Avalonia.Controls.Primitives
         private static readonly Dictionary<KnownColor, string> _cachedKnownColorNames = new Dictionary<KnownColor, string>();
         private static readonly object _displayNameCacheMutex = new object();
         private static readonly object _knownColorCacheMutex = new object();
-        private static readonly KnownColor[] _knownColors = (KnownColor[])Enum.GetValues(typeof(KnownColor));
+        private static readonly KnownColor[] _knownColors =
+#if NET6_0_OR_GREATER
+            Enum.GetValues<KnownColor>();
+#else 
+            (KnownColor[])Enum.GetValues(typeof(KnownColor));
+#endif
 
         /// <summary>
         /// Gets the relative (perceptual) luminance/brightness of the given color.
diff --git a/src/Avalonia.Remote.Protocol/MetsysBson.cs b/src/Avalonia.Remote.Protocol/MetsysBson.cs
index 9c5f92b6ac..390ab8f67d 100644
--- a/src/Avalonia.Remote.Protocol/MetsysBson.cs
+++ b/src/Avalonia.Remote.Protocol/MetsysBson.cs
@@ -73,6 +73,7 @@ namespace Metsys.Bson
 namespace Metsys.Bson
 {
     [RequiresUnreferencedCode("Bson uses reflection")]
+    [UnconditionalSuppressMessage("Trimming", "IL3050", Justification = "Bson uses reflection")]
     internal class Serializer
     {
         private static readonly IDictionary<Type, Types> _typeMap = new Dictionary<Type, Types>
@@ -615,6 +616,8 @@ namespace Metsys.Bson
 
 namespace Metsys.Bson
 {
+    [RequiresUnreferencedCode("Bson uses reflection")]
+    [UnconditionalSuppressMessage("Trimming", "IL3050", Justification = "Bson uses reflection")]
     internal class MagicProperty
     {
         private readonly PropertyInfo _property;
@@ -689,6 +692,7 @@ namespace Metsys.Bson
 namespace Metsys.Bson
 {
     [RequiresUnreferencedCode("Bson uses reflection")]
+    [UnconditionalSuppressMessage("Trimming", "IL3050", Justification = "Bson uses reflection")]
     internal class TypeHelper
     {
         private static readonly IDictionary<Type, TypeHelper> _cachedTypeLookup = new Dictionary<Type, TypeHelper>();
@@ -791,6 +795,7 @@ namespace Metsys.Bson
 namespace Metsys.Bson
 {
     [RequiresUnreferencedCode("Bson uses reflection")]
+    [UnconditionalSuppressMessage("Trimming", "IL3050", Justification = "Bson uses reflection")]
     internal class ListWrapper : BaseWrapper
     {
         private IList _list;
@@ -826,6 +831,7 @@ namespace Metsys.Bson
 namespace Metsys.Bson
 {
     [RequiresUnreferencedCode("Bson uses reflection")]
+    [UnconditionalSuppressMessage("Trimming", "IL3050", Justification = "Bson uses reflection")]
     internal static class ListHelper
     {
         public static Type GetListItemType(Type enumerableType)
@@ -871,6 +877,7 @@ namespace Metsys.Bson
 namespace Metsys.Bson
 {
     [RequiresUnreferencedCode("Bson uses reflection")]
+    [UnconditionalSuppressMessage("Trimming", "IL3050", Justification = "Bson uses reflection")]
     internal class CollectionWrapper<T> : BaseWrapper
     {
         private ICollection<T> _list;
@@ -899,6 +906,7 @@ namespace Metsys.Bson
 namespace Metsys.Bson
 {
     [RequiresUnreferencedCode("Bson uses reflection")]
+    [UnconditionalSuppressMessage("Trimming", "IL3050", Justification = "Bson uses reflection")]
     internal abstract class BaseWrapper
     {
         public static BaseWrapper Create(Type type, Type itemType, object existingContainer)
@@ -956,6 +964,7 @@ namespace Metsys.Bson
 namespace Metsys.Bson
 {
     [RequiresUnreferencedCode("Bson uses reflection")]
+    [UnconditionalSuppressMessage("Trimming", "IL3050", Justification = "Bson uses reflection")]
     internal class ArrayWrapper<T> : BaseWrapper
     {
         private readonly List<T> _list = new List<T>();
@@ -1008,6 +1017,7 @@ namespace Metsys.Bson
 namespace Metsys.Bson
 {
     [RequiresUnreferencedCode("Bson uses reflection")]
+    [UnconditionalSuppressMessage("Trimming", "IL3050", Justification = "Bson uses reflection")]
     internal class Deserializer
     {
         internal class Options
diff --git a/src/Linux/Avalonia.LinuxFramebuffer/Input/EvDev/EvDevDevice.cs b/src/Linux/Avalonia.LinuxFramebuffer/Input/EvDev/EvDevDevice.cs
index e7978a6e23..7bdbaba72a 100644
--- a/src/Linux/Avalonia.LinuxFramebuffer/Input/EvDev/EvDevDevice.cs
+++ b/src/Linux/Avalonia.LinuxFramebuffer/Input/EvDev/EvDevDevice.cs
@@ -20,7 +20,11 @@ namespace Avalonia.LinuxFramebuffer.Input.EvDev
             Fd = fd;
             _dev = dev;
             Name = Marshal.PtrToStringAnsi(NativeUnsafeMethods.libevdev_get_name(_dev));
+#if NET6_0_OR_GREATER
+            foreach (EvType type in Enum.GetValues<EvType>())
+#else 
             foreach (EvType type in Enum.GetValues(typeof(EvType)))
+#endif
             {
                 if (NativeUnsafeMethods.libevdev_has_event_type(dev, type) != 0)
                     EventTypes.Add(type);
diff --git a/src/Markup/Avalonia.Markup.Xaml.Loader/Avalonia.Markup.Xaml.Loader.csproj b/src/Markup/Avalonia.Markup.Xaml.Loader/Avalonia.Markup.Xaml.Loader.csproj
index 532f75e8eb..8569b7ec9a 100644
--- a/src/Markup/Avalonia.Markup.Xaml.Loader/Avalonia.Markup.Xaml.Loader.csproj
+++ b/src/Markup/Avalonia.Markup.Xaml.Loader/Avalonia.Markup.Xaml.Loader.csproj
@@ -3,6 +3,7 @@
   <PropertyGroup>
     <TargetFrameworks>net6.0;netstandard2.0</TargetFrameworks>
     <IsPackable>true</IsPackable>
+    <IsAotCompatible>false</IsAotCompatible>
     <DefineConstants>$(DefineConstants);XAMLX_INTERNAL;XAML_RUNTIME_LOADER</DefineConstants>
   </PropertyGroup>
   <ItemGroup>
diff --git a/src/Markup/Avalonia.Markup.Xaml/MarkupExtensions/CompiledBindings/CompiledBindingPath.cs b/src/Markup/Avalonia.Markup.Xaml/MarkupExtensions/CompiledBindings/CompiledBindingPath.cs
index 7249c389df..6b6e680af6 100644
--- a/src/Markup/Avalonia.Markup.Xaml/MarkupExtensions/CompiledBindings/CompiledBindingPath.cs
+++ b/src/Markup/Avalonia.Markup.Xaml/MarkupExtensions/CompiledBindings/CompiledBindingPath.cs
@@ -255,7 +255,8 @@ namespace Avalonia.Markup.Xaml.MarkupExtensions.CompiledBindings
         {
             Method = MethodBase.GetMethodFromHandle(method) as MethodInfo
                 ?? throw new ArgumentException("Invalid method handle", nameof(method));
-            DelegateType = Type.GetTypeFromHandle(delegateType);
+            DelegateType = Type.GetTypeFromHandle(delegateType)
+                ?? throw new ArgumentException("Unexpected null returned from Type.GetTypeFromHandle in MethodAsDelegateElement");
         }
 
         public MethodInfo Method { get; }
diff --git a/src/Windows/Avalonia.Win32/Avalonia.Win32.csproj b/src/Windows/Avalonia.Win32/Avalonia.Win32.csproj
index 6ec71360a0..27cf5f69bf 100644
--- a/src/Windows/Avalonia.Win32/Avalonia.Win32.csproj
+++ b/src/Windows/Avalonia.Win32/Avalonia.Win32.csproj
@@ -2,6 +2,8 @@
   <PropertyGroup>
     <TargetFrameworks>net6.0;netstandard2.0</TargetFrameworks>
     <AllowUnsafeBlocks>true</AllowUnsafeBlocks>
+    <!-- We still keep BinaryFormatter for WinForms compatibility. -->
+    <EnableUnsafeBinaryFormatterSerialization>true</EnableUnsafeBinaryFormatterSerialization>
   </PropertyGroup>
   <ItemGroup>
     <PackageReference Include="System.Numerics.Vectors" Version="4.5.0" />
diff --git a/src/Windows/Avalonia.Win32/OleDataObject.cs b/src/Windows/Avalonia.Win32/OleDataObject.cs
index 824303b7fa..081bdebb18 100644
--- a/src/Windows/Avalonia.Win32/OleDataObject.cs
+++ b/src/Windows/Avalonia.Win32/OleDataObject.cs
@@ -41,6 +41,7 @@ namespace Avalonia.Win32
         }
 
         [UnconditionalSuppressMessage("Trimming", "IL2026", Justification = "We still use BinaryFormatter for WinForms dragndrop compatability")]
+        [UnconditionalSuppressMessage("Trimming", "IL3050", Justification = "We still use BinaryFormatter for WinForms dragndrop compatability")]
         private unsafe object? GetDataFromOleHGLOBAL(string format, DVASPECT aspect)
         {
             var formatEtc = new Interop.FORMATETC();
@@ -75,8 +76,8 @@ namespace Avalonia.Win32
                             using (var ms = new MemoryStream(data))
                             {
                                 ms.Position = DataObject.SerializedObjectGUID.Length;
-                                BinaryFormatter binaryFormatter = new BinaryFormatter();
 #pragma warning disable SYSLIB0011 // Type or member is obsolete
+                                BinaryFormatter binaryFormatter = new BinaryFormatter();
                                 return binaryFormatter.Deserialize(ms);
 #pragma warning restore SYSLIB0011 // Type or member is obsolete
                             }
diff --git a/src/Windows/Avalonia.Win32/WindowImpl.cs b/src/Windows/Avalonia.Win32/WindowImpl.cs
index 04b7202c39..e34172c7ee 100644
--- a/src/Windows/Avalonia.Win32/WindowImpl.cs
+++ b/src/Windows/Avalonia.Win32/WindowImpl.cs
@@ -1,4 +1,4 @@
-using System;
+using System;
 using System.Collections.Generic;
 using System.ComponentModel;
 using System.Diagnostics.CodeAnalysis;
@@ -536,7 +536,7 @@ namespace Avalonia.Win32
                     return PixelSize.Empty;
                 }
 
-                DwmGetWindowAttribute(_hwnd, (int)DwmWindowAttribute.DWMWA_EXTENDED_FRAME_BOUNDS, out var clientRect, Marshal.SizeOf(typeof(RECT)));
+                DwmGetWindowAttribute(_hwnd, (int)DwmWindowAttribute.DWMWA_EXTENDED_FRAME_BOUNDS, out var clientRect, Marshal.SizeOf<RECT>());
                 GetWindowRect(_hwnd, out var frameRect);
                 var borderWidth = GetSystemMetrics(SystemMetric.SM_CXBORDER);
 
diff --git a/src/tools/Avalonia.Designer.HostApp/Avalonia.Designer.HostApp.csproj b/src/tools/Avalonia.Designer.HostApp/Avalonia.Designer.HostApp.csproj
index d904684ffb..e5d2f14f79 100644
--- a/src/tools/Avalonia.Designer.HostApp/Avalonia.Designer.HostApp.csproj
+++ b/src/tools/Avalonia.Designer.HostApp/Avalonia.Designer.HostApp.csproj
@@ -3,6 +3,7 @@
     <OutputType>Exe</OutputType>
     <TargetFrameworks>net461;netstandard2.0;net6.0</TargetFrameworks>
     <DefineConstants>$(DefineConstants);XAMLX_INTERNAL</DefineConstants>
+    <IsAotCompatible>false</IsAotCompatible>
   </PropertyGroup>
   <ItemGroup>
     <ProjectReference Include="..\..\Avalonia.DesignerSupport\Avalonia.DesignerSupport.csproj" />