diff --git a/src/Avalonia.Controls/ComboBox.cs b/src/Avalonia.Controls/ComboBox.cs
index bce1a3685f..fb27b3da22 100644
--- a/src/Avalonia.Controls/ComboBox.cs
+++ b/src/Avalonia.Controls/ComboBox.cs
@@ -270,6 +270,7 @@ namespace Avalonia.Controls
             {
                 if (_popup?.IsInsidePopup(source) == true)
                 {
+                    e.Handled = true;
                     return;
                 }
             }