diff --git a/src/Avalonia.Controls.DataGrid/DataGridColumnCollection.cs b/src/Avalonia.Controls.DataGrid/DataGridColumnCollection.cs
index 798228c84c..35f400c208 100644
--- a/src/Avalonia.Controls.DataGrid/DataGridColumnCollection.cs
+++ b/src/Avalonia.Controls.DataGrid/DataGridColumnCollection.cs
@@ -237,7 +237,8 @@ namespace Avalonia.Controls
 
         protected override void SetItem(int columnIndex, DataGridColumn dataGridColumn)
         {
-            throw new NotSupportedException();
+            RemoveItem(columnIndex);
+            InsertItem(columnIndex, dataGridColumn);
         }
 
         internal bool DisplayInOrder(int columnIndex1, int columnIndex2)