diff --git a/src/Avalonia.Base/Logging/LogArea.cs b/src/Avalonia.Base/Logging/LogArea.cs
index 139129e623..07553a647e 100644
--- a/src/Avalonia.Base/Logging/LogArea.cs
+++ b/src/Avalonia.Base/Logging/LogArea.cs
@@ -20,6 +20,11 @@ namespace Avalonia.Logging
         /// </summary>
         public const string Animations = nameof(Animations);
 
+        /// <summary>
+        /// The log event comes from the fonts system.
+        /// </summary>
+        public const string Fonts = nameof(Fonts);
+
         /// <summary>
         /// The log event comes from the visual system.
         /// </summary>
diff --git a/src/Avalonia.Base/Media/FontManager.cs b/src/Avalonia.Base/Media/FontManager.cs
index 9d1d0145d0..1f15820b9a 100644
--- a/src/Avalonia.Base/Media/FontManager.cs
+++ b/src/Avalonia.Base/Media/FontManager.cs
@@ -199,7 +199,7 @@ namespace Avalonia.Media
                     return true;
                 }
 
-                var logger = Logger.TryGet(LogEventLevel.Debug, "FontManager");
+                var logger = Logger.TryGet(LogEventLevel.Debug, LogArea.Fonts);
 
                 logger?.Log(this,
                     $"Font family '{familyName}' could not be found. Present font families: [{string.Join(",", fontCollection)}]");
diff --git a/src/Avalonia.Base/Media/Fonts/FontCollectionBase.cs b/src/Avalonia.Base/Media/Fonts/FontCollectionBase.cs
index 4c535bdc0e..a3375652b8 100644
--- a/src/Avalonia.Base/Media/Fonts/FontCollectionBase.cs
+++ b/src/Avalonia.Base/Media/Fonts/FontCollectionBase.cs
@@ -128,7 +128,9 @@ namespace Avalonia.Media.Fonts
                 {
                     if (_fontManagerImpl.TryCreateGlyphTypeface(stream, fontSimulations, out var platformTypeface))
                     {
-                        syntheticGlyphTypeface = new GlyphTypeface(platformTypeface, fontSimulations);
+                        syntheticGlyphTypeface = GlyphTypeface.TryCreate(platformTypeface, fontSimulations);
+                        if (syntheticGlyphTypeface is null)
+                            return false;
 
                         //Add the TypographicFamilyName to the cache
                         if (!string.IsNullOrEmpty(glyphTypeface.TypographicFamilyName))
@@ -272,16 +274,14 @@ namespace Avalonia.Media.Fonts
         /// langword="false"/>.</returns>
         public bool TryAddGlyphTypeface(Stream stream, [NotNullWhen(true)] out GlyphTypeface? glyphTypeface)
         {
-            glyphTypeface = null;
-
             if (!_fontManagerImpl.TryCreateGlyphTypeface(stream, FontSimulations.None, out var platformTypeface))
             {
+                glyphTypeface = null;
                 return false;
             }
 
-            glyphTypeface = new GlyphTypeface(platformTypeface);
-
-            return TryAddGlyphTypeface(glyphTypeface);
+            glyphTypeface = GlyphTypeface.TryCreate(platformTypeface);
+            return glyphTypeface is not null && TryAddGlyphTypeface(glyphTypeface);
         }
 
         /// <summary>
@@ -315,13 +315,12 @@ namespace Avalonia.Media.Fonts
                         {
                             var stream = _assetLoader.Open(fontAsset);
 
-                            if (!_fontManagerImpl.TryCreateGlyphTypeface(stream, FontSimulations.None, out var platformTypeface))
+                            if (!_fontManagerImpl.TryCreateGlyphTypeface(stream, FontSimulations.None, out var platformTypeface) ||
+                                GlyphTypeface.TryCreate(platformTypeface) is not { } glyphTypeface)
                             {
                                 continue;
                             }
 
-                            var glyphTypeface = new GlyphTypeface(platformTypeface);
-
                             var key = glyphTypeface.ToFontCollectionKey();
 
                             //Add TypographicFamilyName to the cache
@@ -353,14 +352,11 @@ namespace Avalonia.Media.Fonts
 
                             using var stream = File.OpenRead(source.LocalPath);
 
-                            if (_fontManagerImpl.TryCreateGlyphTypeface(stream, FontSimulations.None, out var platformTypeface))
+                            if (_fontManagerImpl.TryCreateGlyphTypeface(stream, FontSimulations.None, out var platformTypeface) &&
+                                GlyphTypeface.TryCreate(platformTypeface) is { } glyphTypeface &&
+                                TryAddGlyphTypeface(glyphTypeface))
                             {
-                                var glyphTypeface = new GlyphTypeface(platformTypeface);
-
-                                if (TryAddGlyphTypeface(glyphTypeface))
-                                {
-                                    result = true;
-                                }
+                                result = true;
                             }
                         }
                         // If the path is a directory, load all font files from that directory
@@ -377,14 +373,11 @@ namespace Avalonia.Media.Fonts
                                 {
                                     using var stream = File.OpenRead(file);
 
-                                    if (_fontManagerImpl.TryCreateGlyphTypeface(stream, FontSimulations.None, out var platformTypeface))
+                                    if (_fontManagerImpl.TryCreateGlyphTypeface(stream, FontSimulations.None, out var platformTypeface) &&
+                                        GlyphTypeface.TryCreate(platformTypeface) is { } glyphTypeface &&
+                                        TryAddGlyphTypeface(glyphTypeface))
                                     {
-                                        var glyphTypeface = new GlyphTypeface(platformTypeface);
-
-                                        if (TryAddGlyphTypeface(glyphTypeface))
-                                        {
-                                            result = true;
-                                        }
+                                        result = true;
                                     }
                                 }
                             }
diff --git a/src/Avalonia.Base/Media/Fonts/SystemFontCollection.cs b/src/Avalonia.Base/Media/Fonts/SystemFontCollection.cs
index cf055e5d99..3c81e9890f 100644
--- a/src/Avalonia.Base/Media/Fonts/SystemFontCollection.cs
+++ b/src/Avalonia.Base/Media/Fonts/SystemFontCollection.cs
@@ -52,7 +52,11 @@ namespace Avalonia.Media.Fonts
                 return false;
             }
 
-            glyphTypeface = new GlyphTypeface(platformTypeface);
+            glyphTypeface = GlyphTypeface.TryCreate(platformTypeface);
+            if (glyphTypeface is null)
+            {
+                return false;
+            }
 
             //Add to cache with platform typeface family name first
             TryAddGlyphTypeface(platformTypeface.FamilyName, key, glyphTypeface);
@@ -112,7 +116,10 @@ namespace Avalonia.Media.Fonts
                 }
 
                 // Not in cache yet: create glyph typeface and try to add it.
-                var glyphTypeface = new GlyphTypeface(platformTypeface);
+                if (GlyphTypeface.TryCreate(platformTypeface) is not { } glyphTypeface)
+                {
+                    return false;
+                }
 
                 // Try adding with the platform typeface family name first.
                 TryAddGlyphTypeface(platformTypeface.FamilyName, key, glyphTypeface);
diff --git a/src/Avalonia.Base/Media/GlyphTypeface.cs b/src/Avalonia.Base/Media/GlyphTypeface.cs
index ca8e3fec16..3b3875b5de 100644
--- a/src/Avalonia.Base/Media/GlyphTypeface.cs
+++ b/src/Avalonia.Base/Media/GlyphTypeface.cs
@@ -1,7 +1,7 @@
 using System;
 using System.Collections.Generic;
 using System.Globalization;
-using System.Runtime.CompilerServices;
+using Avalonia.Logging;
 using Avalonia.Media.Fonts;
 using Avalonia.Media.Fonts.Tables;
 using Avalonia.Media.Fonts.Tables.Cmap;
@@ -222,6 +222,25 @@ namespace Avalonia.Media
             }
         }
 
+        internal static GlyphTypeface? TryCreate(IPlatformTypeface typeface, FontSimulations fontSimulations = FontSimulations.None)
+        {
+            try
+            {
+                return new GlyphTypeface(typeface, fontSimulations);
+            }
+            catch (Exception ex)
+            {
+                Logger.TryGet(LogEventLevel.Warning, LogArea.Fonts)?.Log(
+                    null,
+                    "Could not create glyph typeface from platform typeface named {FamilyName} with simulations {Simulations}: {Exception}",
+                    typeface.FamilyName,
+                    fontSimulations,
+                    ex);
+
+                return null;
+            }
+        }
+
         /// <summary>
         /// Gets the family name of the font.
         /// </summary>
diff --git a/tests/Avalonia.Skia.UnitTests/Fonts/TestFontNoCmap412.ttf b/tests/Avalonia.Skia.UnitTests/Fonts/TestFontNoCmap412.ttf
new file mode 100644
index 0000000000..03a0fbe537
Binary files /dev/null and b/tests/Avalonia.Skia.UnitTests/Fonts/TestFontNoCmap412.ttf differ
diff --git a/tests/Avalonia.Skia.UnitTests/Media/FontManagerTests.cs b/tests/Avalonia.Skia.UnitTests/Media/FontManagerTests.cs
index 994edc6095..76d4857e64 100644
--- a/tests/Avalonia.Skia.UnitTests/Media/FontManagerTests.cs
+++ b/tests/Avalonia.Skia.UnitTests/Media/FontManagerTests.cs
@@ -1,10 +1,11 @@
 using System;
 using System.Collections.Generic;
 using Avalonia.Fonts.Inter;
-using Avalonia.Headless;
+using Avalonia.Logging;
 using Avalonia.Media;
 using Avalonia.Media.Fonts;
 using Avalonia.Media.TextFormatting.Unicode;
+using Avalonia.Platform;
 using Avalonia.UnitTests;
 using SkiaSharp;
 using Xunit;
@@ -494,5 +495,53 @@ namespace Avalonia.Skia.UnitTests.Media
                 }
             }
         }
+
+        [Fact]
+        public void TryGetGlyphTypeface_Should_Return_False_For_Font_Without_Supported_Cmap()
+        {
+            const string fontUri = "resm:Avalonia.Skia.UnitTests.Fonts.TestFontNoCmap412.ttf?assembly=Avalonia.Skia.UnitTests#TestFontNoCmap412";
+
+            using var app = UnitTestApplication.Start(TestServices.MockPlatformRenderInterface.With(fontManagerImpl: new FontManagerImpl()));
+            using var scope = AvaloniaLocator.EnterScope();
+
+            // Skia can load the font
+            AssertCanCreatePlatformTypeface();
+
+            // But Avalonia can't, because it has no supported cmap subtable
+            AssertCannotCreateGlyphTypeface();
+
+            void AssertCanCreatePlatformTypeface()
+            {
+                var fontManagerImpl = AvaloniaLocator.Current.GetRequiredService<IFontManagerImpl>();
+                var assetLoader = AvaloniaLocator.Current.GetRequiredService<IAssetLoader>();
+
+                using var stream = assetLoader.Open(new Uri(fontUri));
+
+                Assert.True(fontManagerImpl.TryCreateGlyphTypeface(stream, FontSimulations.None, out var platformTypeface));
+                Assert.NotNull(platformTypeface);
+                Assert.Equal("TestFontNoCmap412", platformTypeface.FamilyName);
+            }
+
+            void AssertCannotCreateGlyphTypeface()
+            {
+                string? loggedTemplate = null;
+                object?[] loggedValues = [];
+
+                using var logSinkScope = TestLogSink.Start((level, area, _, template, values) =>
+                {
+                    if (level == LogEventLevel.Warning && area == LogArea.Fonts)
+                    {
+                        loggedTemplate = template;
+                        loggedValues = values;
+                    }
+                });
+
+                Assert.False(FontManager.Current.TryGetGlyphTypeface(new Typeface(fontUri), out _));
+                Assert.Equal(loggedTemplate, "Could not create glyph typeface from platform typeface named {FamilyName} with simulations {Simulations}: {Exception}");
+                Assert.Equal(3, loggedValues.Length);
+                Assert.Equal("TestFontNoCmap412", Assert.IsType<string>(loggedValues[0]));
+                Assert.Equal("No suitable cmap subtable found.", Assert.IsType<InvalidOperationException>(loggedValues[2]).Message);
+            }
+        }
     }
 }