diff --git a/src/ImageSharp/Dithering/ErrorDiffusion/ErrorDiffuser.cs b/src/ImageSharp/Dithering/ErrorDiffusion/ErrorDiffuser.cs
index 0c4192a87..408e6c383 100644
--- a/src/ImageSharp/Dithering/ErrorDiffusion/ErrorDiffuser.cs
+++ b/src/ImageSharp/Dithering/ErrorDiffusion/ErrorDiffuser.cs
@@ -5,6 +5,7 @@
 
 namespace ImageSharp.Dithering
 {
+    using System;
     using System.Numerics;
     using System.Runtime.CompilerServices;
 
@@ -95,30 +96,33 @@ namespace ImageSharp.Dithering
             for (int row = 0; row < this.matrixHeight; row++)
             {
                 int matrixY = y + row;
-
-                for (int col = 0; col < this.matrixWidth; col++)
+                if (matrixY > 0 && matrixY < height)
                 {
-                    int matrixX = x + (col - this.startingOffset);
+                    Span<TPixel> rowSpan = image.GetRowSpan(matrixY);
 
-                    if (matrixX > 0 && matrixX < width && matrixY > 0 && matrixY < height)
+                    for (int col = 0; col < this.matrixWidth; col++)
                     {
-                        float coefficient = this.matrix[row, col];
+                        int matrixX = x + (col - this.startingOffset);
 
-                        // Good to disable here as we are not comparing mathematical output.
-                        // ReSharper disable once CompareOfFloatsByEqualityOperator
-                        if (coefficient == 0)
+                        if (matrixX > 0 && matrixX < width)
                         {
-                            continue;
+                            float coefficient = this.matrix[row, col];
+
+                            // Good to disable here as we are not comparing mathematical output.
+                            // ReSharper disable once CompareOfFloatsByEqualityOperator
+                            if (coefficient == 0)
+                            {
+                                continue;
+                            }
+
+                            ref TPixel pixel = ref rowSpan[matrixX];
+                            var offsetColor = pixel.ToVector4();
+                            var coefficientVector = new Vector4(coefficient);
+
+                            Vector4 result = ((error * coefficientVector) / this.divisorVector) + offsetColor;
+                            result.W = offsetColor.W;
+                            pixel.PackFromVector4(result);
                         }
-
-                        var coefficientVector = new Vector4(coefficient);
-                        var offsetColor = image[matrixX, matrixY].ToVector4();
-                        Vector4 result = ((error * coefficientVector) / this.divisorVector) + offsetColor;
-                        result.W = offsetColor.W;
-
-                        var packed = default(TPixel);
-                        packed.PackFromVector4(result);
-                        image[matrixX, matrixY] = packed;
                     }
                 }
             }
diff --git a/src/ImageSharp/Processing/Processors/Binarization/ErrorDiffusionDitherProcessor.cs b/src/ImageSharp/Processing/Processors/Binarization/ErrorDiffusionDitherProcessor.cs
index cb6f2fce4..47811f0ec 100644
--- a/src/ImageSharp/Processing/Processors/Binarization/ErrorDiffusionDitherProcessor.cs
+++ b/src/ImageSharp/Processing/Processors/Binarization/ErrorDiffusionDitherProcessor.cs
@@ -88,10 +88,12 @@ namespace ImageSharp.Processing.Processors
             for (int y = minY; y < maxY; y++)
             {
                 int offsetY = y - startY;
+                Span<TPixel> row = source.GetRowSpan(offsetY);
+
                 for (int x = minX; x < maxX; x++)
                 {
                     int offsetX = x - startX;
-                    TPixel sourceColor = source[offsetX, offsetY];
+                    TPixel sourceColor = row[offsetX];
                     TPixel transformedColor = sourceColor.ToVector4().X >= this.Threshold ? this.UpperColor : this.LowerColor;
                     this.Diffuser.Dither(source, sourceColor, transformedColor, offsetX, offsetY, maxX, maxY);
                 }
diff --git a/src/ImageSharp/Quantizers/OctreeQuantizer{TPixel}.cs b/src/ImageSharp/Quantizers/OctreeQuantizer{TPixel}.cs
index f41272900..bd963c452 100644
--- a/src/ImageSharp/Quantizers/OctreeQuantizer{TPixel}.cs
+++ b/src/ImageSharp/Quantizers/OctreeQuantizer{TPixel}.cs
@@ -78,11 +78,13 @@ namespace ImageSharp.Quantizers
 
             for (int y = 0; y < height; y++)
             {
+                Span<TPixel> row = source.GetRowSpan(y);
+
                 // And loop through each column
                 for (int x = 0; x < width; x++)
                 {
                     // Get the pixel.
-                    sourcePixel = source[x, y];
+                    sourcePixel = row[x];
 
                     // Check if this is the same as the last pixel. If so use that value
                     // rather than calculating it again. This is an inexpensive optimization.
diff --git a/src/ImageSharp/Quantizers/PaletteQuantizer{TPixel}.cs b/src/ImageSharp/Quantizers/PaletteQuantizer{TPixel}.cs
index 52d3f320d..cf3ff94ee 100644
--- a/src/ImageSharp/Quantizers/PaletteQuantizer{TPixel}.cs
+++ b/src/ImageSharp/Quantizers/PaletteQuantizer{TPixel}.cs
@@ -84,11 +84,13 @@ namespace ImageSharp.Quantizers
 
             for (int y = 0; y < height; y++)
             {
+                Span<TPixel> row = source.GetRowSpan(y);
+
                 // And loop through each column
                 for (int x = 0; x < width; x++)
                 {
                     // Get the pixel.
-                    sourcePixel = source[x, y];
+                    sourcePixel = row[x];
 
                     // Check if this is the same as the last pixel. If so use that value
                     // rather than calculating it again. This is an inexpensive optimization.
diff --git a/src/ImageSharp/Quantizers/Quantizer{TPixel}.cs b/src/ImageSharp/Quantizers/Quantizer{TPixel}.cs
index e99402996..2e3ea7a54 100644
--- a/src/ImageSharp/Quantizers/Quantizer{TPixel}.cs
+++ b/src/ImageSharp/Quantizers/Quantizer{TPixel}.cs
@@ -5,6 +5,7 @@
 
 namespace ImageSharp.Quantizers
 {
+    using System;
     using System.Collections.Generic;
     using System.Numerics;
     using System.Runtime.CompilerServices;
@@ -93,11 +94,13 @@ namespace ImageSharp.Quantizers
             // Loop through each row
             for (int y = 0; y < height; y++)
             {
+                Span<TPixel> row = source.GetRowSpan(y);
+
                 // And loop through each column
                 for (int x = 0; x < width; x++)
                 {
                     // Now I have the pixel, call the FirstPassQuantize function...
-                    this.InitialQuantizePixel(source[x, y]);
+                    this.InitialQuantizePixel(row[x]);
                 }
             }
         }
diff --git a/src/ImageSharp/Quantizers/WuQuantizer{TPixel}.cs b/src/ImageSharp/Quantizers/WuQuantizer{TPixel}.cs
index 8d98a29d8..aecca771c 100644
--- a/src/ImageSharp/Quantizers/WuQuantizer{TPixel}.cs
+++ b/src/ImageSharp/Quantizers/WuQuantizer{TPixel}.cs
@@ -252,11 +252,13 @@ namespace ImageSharp.Quantizers
 
             for (int y = 0; y < height; y++)
             {
+                Span<TPixel> row = source.GetRowSpan(y);
+
                 // And loop through each column
                 for (int x = 0; x < width; x++)
                 {
                     // Get the pixel.
-                    sourcePixel = source[x, y];
+                    sourcePixel = row[x];
 
                     // Check if this is the same as the last pixel. If so use that value
                     // rather than calculating it again. This is an inexpensive optimization.