diff --git a/src/ImageSharp/Formats/Tiff/TiffEncoderCompression.cs b/src/ImageSharp/Formats/Tiff/TiffEncoderCompression.cs
index 334262dbfc..536cd2c2d3 100644
--- a/src/ImageSharp/Formats/Tiff/TiffEncoderCompression.cs
+++ b/src/ImageSharp/Formats/Tiff/TiffEncoderCompression.cs
@@ -12,5 +12,10 @@ namespace SixLabors.ImageSharp.Formats.Tiff
         /// No compression is used.
         /// </summary>
         None,
+
+        /// <summary>
+        /// Use zlib compression.
+        /// </summary>
+        Deflate
     }
 }
diff --git a/src/ImageSharp/Formats/Tiff/TiffEncoderCore.cs b/src/ImageSharp/Formats/Tiff/TiffEncoderCore.cs
index c493d34a41..99b299d043 100644
--- a/src/ImageSharp/Formats/Tiff/TiffEncoderCore.cs
+++ b/src/ImageSharp/Formats/Tiff/TiffEncoderCore.cs
@@ -150,16 +150,16 @@ namespace SixLabors.ImageSharp.Formats.Tiff
             // Write the image bytes to the steam.
             var imageDataStart = (uint)writer.Position;
             int imageDataBytes;
-            switch (this.PhotometricInterpretation)
+            switch (this.Mode)
             {
-                case TiffPhotometricInterpretation.PaletteColor:
+                case TiffEncodingMode.ColorPalette:
                     imageDataBytes = writer.WritePalettedRgbImageData(image, this.quantizer, this.padding, out colorMap);
                     break;
-                case TiffPhotometricInterpretation.BlackIsZero:
+                case TiffEncodingMode.Gray:
                     imageDataBytes = writer.WriteGrayImageData(image, this.padding);
                     break;
                 default:
-                    imageDataBytes = writer.WriteRgbImageData(image, this.padding);
+                    imageDataBytes = writer.WriteRgbImageData(image, this.padding, this.CompressionType);
                     break;
             }
 
@@ -260,10 +260,10 @@ namespace SixLabors.ImageSharp.Formats.Tiff
                 Value = bitsPerSampleValue
             };
 
+            ushort compressionType = this.GetCompressionType();
             var compression = new ExifShort(ExifTagValue.Compression)
             {
-                // TODO: for the start, no compression is used.
-                Value = (ushort)TiffCompression.None
+                Value = compressionType
             };
 
             var photometricInterpretation = new ExifShort(ExifTagValue.PhotometricInterpretation)
@@ -374,5 +374,16 @@ namespace SixLabors.ImageSharp.Formats.Tiff
                     return new ushort[] { 8, 8, 8 };
             }
         }
+
+        private ushort GetCompressionType()
+        {
+            if (this.CompressionType == TiffEncoderCompression.Deflate &&
+                this.PhotometricInterpretation == TiffPhotometricInterpretation.Rgb)
+            {
+                return (ushort)TiffCompression.Deflate;
+            }
+
+            return (ushort)TiffCompression.None;
+        }
     }
 }
diff --git a/src/ImageSharp/Formats/Tiff/Utils/TiffWriter.cs b/src/ImageSharp/Formats/Tiff/Utils/TiffWriter.cs
index e99682bc08..8ef57f4b2a 100644
--- a/src/ImageSharp/Formats/Tiff/Utils/TiffWriter.cs
+++ b/src/ImageSharp/Formats/Tiff/Utils/TiffWriter.cs
@@ -6,6 +6,9 @@ using System.Buffers;
 using System.Collections.Generic;
 using System.IO;
 using System.Runtime.InteropServices;
+
+using SixLabors.ImageSharp.Formats.Png;
+using SixLabors.ImageSharp.Formats.Png.Zlib;
 using SixLabors.ImageSharp.Memory;
 using SixLabors.ImageSharp.Metadata.Profiles.Exif;
 using SixLabors.ImageSharp.PixelFormats;
@@ -133,13 +136,37 @@ namespace SixLabors.ImageSharp.Formats.Tiff
         /// <typeparam name="TPixel">The pixel data.</typeparam>
         /// <param name="image">The image to write to the stream.</param>
         /// <param name="padding">The padding bytes for each row.</param>
+        /// <param name="compression">The compression to use.</param>
         /// <returns>The number of bytes written.</returns>
-        public int WriteRgbImageData<TPixel>(Image<TPixel> image, int padding)
+        public int WriteRgbImageData<TPixel>(Image<TPixel> image, int padding, TiffEncoderCompression compression)
             where TPixel : unmanaged, IPixel<TPixel>
         {
             using IManagedByteBuffer row = this.AllocateRow(image.Width, 3, padding);
             Span<byte> rowSpan = row.GetSpan();
             int bytesWritten = 0;
+            if (compression == TiffEncoderCompression.Deflate)
+            {
+                using var memoryStream = new MemoryStream();
+
+                // TODO: move zlib compression from png to a common place?
+                using var deflateStream = new ZlibDeflateStream(this.memoryAllocator, memoryStream, PngCompressionLevel.Level6); // TODO: make compression level configurable
+
+                for (int y = 0; y < image.Height; y++)
+                {
+                    Span<TPixel> pixelRow = image.GetPixelRowSpan(y);
+                    PixelOperations<TPixel>.Instance.ToRgb24Bytes(this.configuration, pixelRow, rowSpan, pixelRow.Length);
+                    deflateStream.Write(rowSpan);
+                }
+
+                deflateStream.Flush();
+
+                byte[] buffer = memoryStream.ToArray();
+                this.output.Write(buffer);
+                bytesWritten += buffer.Length;
+                return bytesWritten;
+            }
+
+            // No compression.
             for (int y = 0; y < image.Height; y++)
             {
                 Span<TPixel> pixelRow = image.GetPixelRowSpan(y);
diff --git a/tests/ImageSharp.Tests/Formats/Tiff/TiffEncoderTests.cs b/tests/ImageSharp.Tests/Formats/Tiff/TiffEncoderTests.cs
index 27ca717e66..cef8cecc7e 100644
--- a/tests/ImageSharp.Tests/Formats/Tiff/TiffEncoderTests.cs
+++ b/tests/ImageSharp.Tests/Formats/Tiff/TiffEncoderTests.cs
@@ -3,10 +3,11 @@
 
 using System.IO;
 
+using SixLabors.ImageSharp.Formats;
 using SixLabors.ImageSharp.Formats.Tiff;
 using SixLabors.ImageSharp.PixelFormats;
 using SixLabors.ImageSharp.Tests.TestUtilities.ImageComparison;
-
+using SixLabors.ImageSharp.Tests.TestUtilities.ReferenceCodecs;
 using Xunit;
 
 namespace SixLabors.ImageSharp.Tests.Formats.Tiff
@@ -14,7 +15,7 @@ namespace SixLabors.ImageSharp.Tests.Formats.Tiff
     [Trait("Category", "Tiff")]
     public class TiffEncoderTests
     {
-        private static TiffDecoder referenceDecoder = new TiffDecoder();
+        private static readonly IImageDecoder ReferenceDecoder = new MagickReferenceDecoder();
 
         public static readonly TheoryData<string, TiffBitsPerPixel> TiffBitsPerPixelFiles =
             new TheoryData<string, TiffBitsPerPixel>
@@ -45,18 +46,23 @@ namespace SixLabors.ImageSharp.Tests.Formats.Tiff
 
         [Theory]
         [WithFile(TestImages.Tiff.RgbUncompressed, PixelTypes.Rgba32)]
-        public void TiffEncoder_EncodeRgb_Works<TPixel>(TestImageProvider<TPixel> provider, TiffBitsPerPixel bitsPerPixel = TiffBitsPerPixel.Pixel24, TiffEncodingMode mode = TiffEncodingMode.Rgb)
-            where TPixel : unmanaged, IPixel<TPixel> => TestTiffEncoderCore(provider, bitsPerPixel, mode);
+        public void TiffEncoder_EncodeRgb_Works<TPixel>(TestImageProvider<TPixel> provider)
+            where TPixel : unmanaged, IPixel<TPixel> => TestTiffEncoderCore(provider, TiffBitsPerPixel.Pixel24, TiffEncodingMode.Rgb);
 
         [Theory]
         [WithFile(TestImages.Tiff.RgbUncompressed, PixelTypes.Rgba32)]
-        public void TiffEncoder_EncodeGray_Works<TPixel>(TestImageProvider<TPixel> provider, TiffBitsPerPixel bitsPerPixel = TiffBitsPerPixel.Pixel8, TiffEncodingMode mode = TiffEncodingMode.Gray)
-            where TPixel : unmanaged, IPixel<TPixel> => TestTiffEncoderCore(provider, bitsPerPixel, mode);
+        public void TiffEncoder_EncodeRgb_WithDeflateCompression_Works<TPixel>(TestImageProvider<TPixel> provider)
+            where TPixel : unmanaged, IPixel<TPixel> => TestTiffEncoderCore(provider, TiffBitsPerPixel.Pixel24, TiffEncodingMode.Rgb, TiffEncoderCompression.Deflate);
+
+        [Theory]
+        [WithFile(TestImages.Tiff.GrayscaleUncompressed, PixelTypes.Rgba32)]
+        public void TiffEncoder_EncodeGray_Works<TPixel>(TestImageProvider<TPixel> provider)
+            where TPixel : unmanaged, IPixel<TPixel> => TestTiffEncoderCore(provider, TiffBitsPerPixel.Pixel8, TiffEncodingMode.Gray);
 
         [Theory]
         [WithFile(TestImages.Tiff.RgbUncompressed, PixelTypes.Rgba32)]
-        public void TiffEncoder_EncodeColorPalette_Works<TPixel>(TestImageProvider<TPixel> provider, TiffBitsPerPixel bitsPerPixel = TiffBitsPerPixel.Pixel24, TiffEncodingMode mode = TiffEncodingMode.ColorPalette)
-            where TPixel : unmanaged, IPixel<TPixel> => TestTiffEncoderCore(provider, bitsPerPixel, mode);
+        public void TiffEncoder_EncodeColorPalette_Works<TPixel>(TestImageProvider<TPixel> provider)
+            where TPixel : unmanaged, IPixel<TPixel> => TestTiffEncoderCore(provider, TiffBitsPerPixel.Pixel24, TiffEncodingMode.ColorPalette);
 
         private static void TestTiffEncoderCore<TPixel>(
             TestImageProvider<TPixel> provider,
@@ -71,7 +77,7 @@ namespace SixLabors.ImageSharp.Tests.Formats.Tiff
             var encoder = new TiffEncoder { Mode = mode, Compression = compression };
 
             // Does DebugSave & load reference CompareToReferenceInput():
-            image.VerifyEncoder(provider, "tiff", bitsPerPixel, encoder, useExactComparer ? ImageComparer.Exact : ImageComparer.Tolerant(compareTolerance), referenceDecoder: referenceDecoder);
+            image.VerifyEncoder(provider, "tiff", bitsPerPixel, encoder, useExactComparer ? ImageComparer.Exact : ImageComparer.Tolerant(compareTolerance), referenceDecoder: ReferenceDecoder);
         }
     }
 }