diff --git a/src/ImageSharp/Formats/Webp/Lossy/Vp8Residual.cs b/src/ImageSharp/Formats/Webp/Lossy/Vp8Residual.cs
index 4eeeedd376..8da176e770 100644
--- a/src/ImageSharp/Formats/Webp/Lossy/Vp8Residual.cs
+++ b/src/ImageSharp/Formats/Webp/Lossy/Vp8Residual.cs
@@ -3,6 +3,11 @@
 
 using System;
 using System.Runtime.CompilerServices;
+using System.Runtime.InteropServices;
+#if SUPPORTS_RUNTIME_INTRINSICS
+using System.Runtime.Intrinsics;
+using System.Runtime.Intrinsics.X86;
+#endif
 
 namespace SixLabors.ImageSharp.Formats.Webp.Lossy
 {
@@ -11,6 +16,16 @@ namespace SixLabors.ImageSharp.Formats.Webp.Lossy
     /// </summary>
     internal class Vp8Residual
     {
+#if SUPPORTS_RUNTIME_INTRINSICS
+        private static readonly Vector128<byte> Cst2 = Vector128.Create((byte)2);
+
+        private static readonly Vector128<byte> Cst67 = Vector128.Create((byte)67);
+#endif
+
+        private readonly byte[] scratch = new byte[32];
+
+        private readonly ushort[] scratchUShort = new ushort[16];
+
         public int First { get; set; }
 
         public int Last { get; set; }
@@ -129,27 +144,82 @@ namespace SixLabors.ImageSharp.Formats.Webp.Lossy
                 return LossyUtils.Vp8BitCost(0, (byte)p0);
             }
 
-            int v;
-            for (; n < this.Last; ++n)
+#if SUPPORTS_RUNTIME_INTRINSICS
+            if (Sse2.IsSupported)
             {
+                Span<byte> ctxs = this.scratch.AsSpan(0, 16);
+                Span<byte> levels = this.scratch.AsSpan(16, 16);
+                Span<ushort> absLevels = this.scratchUShort.AsSpan();
+
+                // Precompute clamped levels and contexts, packed to 8b.
+                ref short outputRef = ref MemoryMarshal.GetReference<short>(this.Coeffs);
+                Vector128<short> c0 = Unsafe.As<short, Vector128<byte>>(ref outputRef).AsInt16();
+                Vector128<short> c1 = Unsafe.As<short, Vector128<byte>>(ref Unsafe.Add(ref outputRef, 8)).AsInt16();
+                Vector128<short> d0 = Sse2.Subtract(Vector128<short>.Zero, c0);
+                Vector128<short> d1 = Sse2.Subtract(Vector128<short>.Zero, c1);
+                Vector128<short> e0 = Sse2.Max(c0, d0); // abs(v), 16b
+                Vector128<short> e1 = Sse2.Max(c1, d1);
+                Vector128<sbyte> f = Sse2.PackSignedSaturate(e0, e1);
+                Vector128<byte> g = Sse2.Min(f.AsByte(), Cst2);
+                Vector128<byte> h = Sse2.Min(f.AsByte(), Cst67); // clampLevel in [0..67]
+
+                ref byte ctxsRef = ref MemoryMarshal.GetReference(ctxs);
+                ref byte levelsRef = ref MemoryMarshal.GetReference(levels);
+                ref ushort absLevelsRef = ref MemoryMarshal.GetReference(absLevels);
+                Unsafe.As<byte, Vector128<byte>>(ref ctxsRef) = g;
+                Unsafe.As<byte, Vector128<byte>>(ref levelsRef) = h;
+                Unsafe.As<ushort, Vector128<ushort>>(ref absLevelsRef) = e0.AsUInt16();
+                Unsafe.As<ushort, Vector128<ushort>>(ref Unsafe.Add(ref absLevelsRef, 8)) = e1.AsUInt16();
+
+                int level;
+                int flevel;
+                for (; n < this.Last; ++n)
+                {
+                    int ctx = ctxs[n];
+                    level = levels[n];
+                    flevel = absLevels[n];
+                    cost += WebpLookupTables.Vp8LevelFixedCosts[flevel] + t.Costs[level];
+                    t = costs[n + 1].Costs[ctx];
+                }
+
+                // Last coefficient is always non-zero.
+                level = levels[n];
+                flevel = absLevels[n];
+                cost += WebpLookupTables.Vp8LevelFixedCosts[flevel] + t.Costs[level];
+                if (n < 15)
+                {
+                    int b = WebpConstants.Vp8EncBands[n + 1];
+                    int ctx = ctxs[n];
+                    int lastP0 = this.Prob[b].Probabilities[ctx].Probabilities[0];
+                    cost += LossyUtils.Vp8BitCost(0, (byte)lastP0);
+                }
+
+                return cost;
+            }
+#endif
+            {
+                int v;
+                for (; n < this.Last; ++n)
+                {
+                    v = Math.Abs(this.Coeffs[n]);
+                    int ctx = v >= 2 ? 2 : v;
+                    cost += LevelCost(t.Costs, v);
+                    t = costs[n + 1].Costs[ctx];
+                }
+
+                // Last coefficient is always non-zero
                 v = Math.Abs(this.Coeffs[n]);
-                int ctx = v >= 2 ? 2 : v;
                 cost += LevelCost(t.Costs, v);
-                t = costs[n + 1].Costs[ctx];
-            }
+                if (n < 15)
+                {
+                    int b = WebpConstants.Vp8EncBands[n + 1];
+                    int ctx = v == 1 ? 1 : 2;
+                    int lastP0 = this.Prob[b].Probabilities[ctx].Probabilities[0];
+                    cost += LossyUtils.Vp8BitCost(0, (byte)lastP0);
+                }
 
-            // Last coefficient is always non-zero
-            v = Math.Abs(this.Coeffs[n]);
-            cost += LevelCost(t.Costs, v);
-            if (n < 15)
-            {
-                int b = WebpConstants.Vp8EncBands[n + 1];
-                int ctx = v == 1 ? 1 : 2;
-                int lastP0 = this.Prob[b].Probabilities[ctx].Probabilities[0];
-                cost += LossyUtils.Vp8BitCost(0, (byte)lastP0);
+                return cost;
             }
-
-            return cost;
         }
 
         [MethodImpl(InliningOptions.ShortMethod)]