diff --git a/src/ImageSharp/Advanced/AotCompilerTools.cs b/src/ImageSharp/Advanced/AotCompilerTools.cs
index 23ae62c7a..d692292b0 100644
--- a/src/ImageSharp/Advanced/AotCompilerTools.cs
+++ b/src/ImageSharp/Advanced/AotCompilerTools.cs
@@ -112,7 +112,7 @@ namespace SixLabors.ImageSharp.Advanced
         private static void AotCompileOctreeQuantizer<TPixel>()
             where TPixel : unmanaged, IPixel<TPixel>
         {
-            using (var test = new OctreeFrameQuantizer<TPixel>(Configuration.Default, new OctreeQuantizer().Options))
+            using (var test = new OctreeQuantizer<TPixel>(Configuration.Default, new OctreeQuantizer().Options))
             {
                 var frame = new ImageFrame<TPixel>(Configuration.Default, 1, 1);
                 test.QuantizeFrame(frame, frame.Bounds());
@@ -126,7 +126,7 @@ namespace SixLabors.ImageSharp.Advanced
         private static void AotCompileWuQuantizer<TPixel>()
             where TPixel : unmanaged, IPixel<TPixel>
         {
-            using (var test = new WuFrameQuantizer<TPixel>(Configuration.Default, new WuQuantizer().Options))
+            using (var test = new WuQuantizer<TPixel>(Configuration.Default, new WuQuantizer().Options))
             {
                 var frame = new ImageFrame<TPixel>(Configuration.Default, 1, 1);
                 test.QuantizeFrame(frame, frame.Bounds());
@@ -140,7 +140,7 @@ namespace SixLabors.ImageSharp.Advanced
         private static void AotCompilePaletteQuantizer<TPixel>()
             where TPixel : unmanaged, IPixel<TPixel>
         {
-            using (var test = (PaletteFrameQuantizer<TPixel>)new PaletteQuantizer(Array.Empty<Color>()).CreateFrameQuantizer<TPixel>(Configuration.Default))
+            using (var test = (PaletteQuantizer<TPixel>)new PaletteQuantizer(Array.Empty<Color>()).CreatePixelSpecificQuantizer<TPixel>(Configuration.Default))
             {
                 var frame = new ImageFrame<TPixel>(Configuration.Default, 1, 1);
                 test.QuantizeFrame(frame, frame.Bounds());
diff --git a/src/ImageSharp/Formats/Bmp/BmpEncoderCore.cs b/src/ImageSharp/Formats/Bmp/BmpEncoderCore.cs
index 7d2799503..c7c53037f 100644
--- a/src/ImageSharp/Formats/Bmp/BmpEncoderCore.cs
+++ b/src/ImageSharp/Formats/Bmp/BmpEncoderCore.cs
@@ -336,7 +336,7 @@ namespace SixLabors.ImageSharp.Formats.Bmp
         private void Write8BitColor<TPixel>(Stream stream, ImageFrame<TPixel> image, Span<byte> colorPalette)
             where TPixel : unmanaged, IPixel<TPixel>
         {
-            using IFrameQuantizer<TPixel> frameQuantizer = this.quantizer.CreateFrameQuantizer<TPixel>(this.configuration);
+            using IQuantizer<TPixel> frameQuantizer = this.quantizer.CreatePixelSpecificQuantizer<TPixel>(this.configuration);
             using IndexedImageFrame<TPixel> quantized = frameQuantizer.QuantizeFrame(image, image.Bounds());
 
             ReadOnlySpan<TPixel> quantizedColors = quantized.Palette.Span;
diff --git a/src/ImageSharp/Formats/Gif/GifEncoderCore.cs b/src/ImageSharp/Formats/Gif/GifEncoderCore.cs
index 62410025c..ae5f62443 100644
--- a/src/ImageSharp/Formats/Gif/GifEncoderCore.cs
+++ b/src/ImageSharp/Formats/Gif/GifEncoderCore.cs
@@ -81,7 +81,7 @@ namespace SixLabors.ImageSharp.Formats.Gif
 
             // Quantize the image returning a palette.
             IndexedImageFrame<TPixel> quantized;
-            using (IFrameQuantizer<TPixel> frameQuantizer = this.quantizer.CreateFrameQuantizer<TPixel>(this.configuration))
+            using (IQuantizer<TPixel> frameQuantizer = this.quantizer.CreatePixelSpecificQuantizer<TPixel>(this.configuration))
             {
                 quantized = frameQuantizer.QuantizeFrame(image.Frames.RootFrame, image.Bounds());
             }
@@ -154,7 +154,7 @@ namespace SixLabors.ImageSharp.Formats.Gif
                         pixelMap = new EuclideanPixelMap<TPixel>(this.configuration, quantized.Palette);
                     }
 
-                    using var paletteFrameQuantizer = new PaletteFrameQuantizer<TPixel>(this.configuration, this.quantizer.Options, pixelMap);
+                    using var paletteFrameQuantizer = new PaletteQuantizer<TPixel>(this.configuration, this.quantizer.Options, pixelMap);
                     using IndexedImageFrame<TPixel> paletteQuantized = paletteFrameQuantizer.QuantizeFrame(frame, frame.Bounds());
                     this.WriteImageData(paletteQuantized, stream);
                 }
@@ -184,12 +184,12 @@ namespace SixLabors.ImageSharp.Formats.Gif
                             MaxColors = frameMetadata.ColorTableLength
                         };
 
-                        using IFrameQuantizer<TPixel> frameQuantizer = this.quantizer.CreateFrameQuantizer<TPixel>(this.configuration, options);
+                        using IQuantizer<TPixel> frameQuantizer = this.quantizer.CreatePixelSpecificQuantizer<TPixel>(this.configuration, options);
                         quantized = frameQuantizer.QuantizeFrame(frame, frame.Bounds());
                     }
                     else
                     {
-                        using IFrameQuantizer<TPixel> frameQuantizer = this.quantizer.CreateFrameQuantizer<TPixel>(this.configuration);
+                        using IQuantizer<TPixel> frameQuantizer = this.quantizer.CreatePixelSpecificQuantizer<TPixel>(this.configuration);
                         quantized = frameQuantizer.QuantizeFrame(frame, frame.Bounds());
                     }
                 }
diff --git a/src/ImageSharp/Formats/Png/PngEncoderOptionsHelpers.cs b/src/ImageSharp/Formats/Png/PngEncoderOptionsHelpers.cs
index 3f490ca6f..8cfd2af35 100644
--- a/src/ImageSharp/Formats/Png/PngEncoderOptionsHelpers.cs
+++ b/src/ImageSharp/Formats/Png/PngEncoderOptionsHelpers.cs
@@ -77,7 +77,7 @@ namespace SixLabors.ImageSharp.Formats.Png
             }
 
             // Create quantized frame returning the palette and set the bit depth.
-            using (IFrameQuantizer<TPixel> frameQuantizer = options.Quantizer.CreateFrameQuantizer<TPixel>(image.GetConfiguration()))
+            using (IQuantizer<TPixel> frameQuantizer = options.Quantizer.CreatePixelSpecificQuantizer<TPixel>(image.GetConfiguration()))
             {
                 ImageFrame<TPixel> frame = image.Frames.RootFrame;
                 return frameQuantizer.QuantizeFrame(frame, frame.Bounds());
diff --git a/src/ImageSharp/Processing/Processors/Dithering/ErrorDither.cs b/src/ImageSharp/Processing/Processors/Dithering/ErrorDither.cs
index 7d30bada6..e322afb8d 100644
--- a/src/ImageSharp/Processing/Processors/Dithering/ErrorDither.cs
+++ b/src/ImageSharp/Processing/Processors/Dithering/ErrorDither.cs
@@ -93,7 +93,7 @@ namespace SixLabors.ImageSharp.Processing.Processors.Dithering
             ImageFrame<TPixel> source,
             IndexedImageFrame<TPixel> destination,
             Rectangle bounds)
-            where TFrameQuantizer : struct, IFrameQuantizer<TPixel>
+            where TFrameQuantizer : struct, IQuantizer<TPixel>
             where TPixel : unmanaged, IPixel<TPixel>
         {
             int offsetY = bounds.Top;
diff --git a/src/ImageSharp/Processing/Processors/Dithering/IDither.cs b/src/ImageSharp/Processing/Processors/Dithering/IDither.cs
index 8f9d82537..8b0e1b8a8 100644
--- a/src/ImageSharp/Processing/Processors/Dithering/IDither.cs
+++ b/src/ImageSharp/Processing/Processors/Dithering/IDither.cs
@@ -26,7 +26,7 @@ namespace SixLabors.ImageSharp.Processing.Processors.Dithering
             ImageFrame<TPixel> source,
             IndexedImageFrame<TPixel> destination,
             Rectangle bounds)
-            where TFrameQuantizer : struct, IFrameQuantizer<TPixel>
+            where TFrameQuantizer : struct, IQuantizer<TPixel>
             where TPixel : unmanaged, IPixel<TPixel>;
 
         /// <summary>
diff --git a/src/ImageSharp/Processing/Processors/Dithering/OrderedDither.cs b/src/ImageSharp/Processing/Processors/Dithering/OrderedDither.cs
index 6862cff00..0f5a7fb55 100644
--- a/src/ImageSharp/Processing/Processors/Dithering/OrderedDither.cs
+++ b/src/ImageSharp/Processing/Processors/Dithering/OrderedDither.cs
@@ -108,7 +108,7 @@ namespace SixLabors.ImageSharp.Processing.Processors.Dithering
             ImageFrame<TPixel> source,
             IndexedImageFrame<TPixel> destination,
             Rectangle bounds)
-            where TFrameQuantizer : struct, IFrameQuantizer<TPixel>
+            where TFrameQuantizer : struct, IQuantizer<TPixel>
             where TPixel : unmanaged, IPixel<TPixel>
         {
             var ditherOperation = new QuantizeDitherRowOperation<TFrameQuantizer, TPixel>(
@@ -195,7 +195,7 @@ namespace SixLabors.ImageSharp.Processing.Processors.Dithering
             => HashCode.Combine(this.thresholdMatrix, this.modulusX, this.modulusY);
 
         private readonly struct QuantizeDitherRowOperation<TFrameQuantizer, TPixel> : IRowOperation
-            where TFrameQuantizer : struct, IFrameQuantizer<TPixel>
+            where TFrameQuantizer : struct, IQuantizer<TPixel>
             where TPixel : unmanaged, IPixel<TPixel>
         {
             private readonly TFrameQuantizer quantizer;
diff --git a/src/ImageSharp/Processing/Processors/Quantization/FrameQuantizerUtilities.cs b/src/ImageSharp/Processing/Processors/Quantization/FrameQuantizerUtilities.cs
index 4d75042ea..c74ea4959 100644
--- a/src/ImageSharp/Processing/Processors/Quantization/FrameQuantizerUtilities.cs
+++ b/src/ImageSharp/Processing/Processors/Quantization/FrameQuantizerUtilities.cs
@@ -11,7 +11,7 @@ using SixLabors.ImageSharp.Processing.Processors.Dithering;
 namespace SixLabors.ImageSharp.Processing.Processors.Quantization
 {
     /// <summary>
-    /// Contains utility methods for <see cref="IFrameQuantizer{TPixel}"/> instances.
+    /// Contains utility methods for <see cref="IQuantizer{TPixel}"/> instances.
     /// </summary>
     public static class FrameQuantizerUtilities
     {
@@ -22,7 +22,7 @@ namespace SixLabors.ImageSharp.Processing.Processors.Quantization
         /// <typeparam name="TPixel">The pixel format.</typeparam>
         /// <param name="palette">The frame quantizer palette.</param>
         /// <exception cref="InvalidOperationException">
-        /// The palette has not been built via <see cref="IFrameQuantizer{TPixel}.BuildPalette(ImageFrame{TPixel}, Rectangle)"/>
+        /// The palette has not been built via <see cref="IQuantizer{TPixel}.CollectPaletteColors"/>
         /// </exception>
         public static void CheckPaletteState<TPixel>(in ReadOnlyMemory<TPixel> palette)
             where TPixel : unmanaged, IPixel<TPixel>
@@ -48,14 +48,15 @@ namespace SixLabors.ImageSharp.Processing.Processors.Quantization
             ref TFrameQuantizer quantizer,
             ImageFrame<TPixel> source,
             Rectangle bounds)
-            where TFrameQuantizer : struct, IFrameQuantizer<TPixel>
+            where TFrameQuantizer : struct, IQuantizer<TPixel>
             where TPixel : unmanaged, IPixel<TPixel>
         {
             Guard.NotNull(source, nameof(source));
             var interest = Rectangle.Intersect(source.Bounds(), bounds);
+            BufferRegion<TPixel> region = source.PixelBuffer.GetRegion(interest);
 
             // Collect the palette. Required before the second pass runs.
-            quantizer.BuildPalette(source, interest);
+            quantizer.CollectPaletteColors(region);
 
             var destination = new IndexedImageFrame<TPixel>(
                 quantizer.Configuration,
@@ -83,7 +84,7 @@ namespace SixLabors.ImageSharp.Processing.Processors.Quantization
             ImageFrame<TPixel> source,
             IndexedImageFrame<TPixel> destination,
             Rectangle bounds)
-            where TFrameQuantizer : struct, IFrameQuantizer<TPixel>
+            where TFrameQuantizer : struct, IQuantizer<TPixel>
             where TPixel : unmanaged, IPixel<TPixel>
         {
             IDither dither = quantizer.Options.Dither;
@@ -108,7 +109,7 @@ namespace SixLabors.ImageSharp.Processing.Processors.Quantization
         }
 
         private readonly struct RowIntervalOperation<TFrameQuantizer, TPixel> : IRowIntervalOperation
-            where TFrameQuantizer : struct, IFrameQuantizer<TPixel>
+            where TFrameQuantizer : struct, IQuantizer<TPixel>
             where TPixel : unmanaged, IPixel<TPixel>
         {
             private readonly TFrameQuantizer quantizer;
diff --git a/src/ImageSharp/Processing/Processors/Quantization/IFrameQuantizer{TPixel}.cs b/src/ImageSharp/Processing/Processors/Quantization/IFrameQuantizer{TPixel}.cs
index cc87715eb..33ba61747 100644
--- a/src/ImageSharp/Processing/Processors/Quantization/IFrameQuantizer{TPixel}.cs
+++ b/src/ImageSharp/Processing/Processors/Quantization/IFrameQuantizer{TPixel}.cs
@@ -2,6 +2,7 @@
 // Licensed under the Apache License, Version 2.0.
 
 using System;
+using SixLabors.ImageSharp.Memory;
 using SixLabors.ImageSharp.PixelFormats;
 
 namespace SixLabors.ImageSharp.Processing.Processors.Quantization
@@ -10,7 +11,7 @@ namespace SixLabors.ImageSharp.Processing.Processors.Quantization
     /// Provides methods to allow the execution of the quantization process on an image frame.
     /// </summary>
     /// <typeparam name="TPixel">The pixel format.</typeparam>
-    public interface IFrameQuantizer<TPixel> : IDisposable
+    public interface IQuantizer<TPixel> : IDisposable
         where TPixel : unmanaged, IPixel<TPixel>
     {
         /// <summary>
@@ -27,16 +28,15 @@ namespace SixLabors.ImageSharp.Processing.Processors.Quantization
         /// Gets the quantized color palette.
         /// </summary>
         /// <exception cref="InvalidOperationException">
-        /// The palette has not been built via <see cref="BuildPalette(ImageFrame{TPixel}, Rectangle)"/>.
+        /// The palette has not been built via <see cref="CollectPaletteColors"/>.
         /// </exception>
         ReadOnlyMemory<TPixel> Palette { get; }
 
         /// <summary>
-        /// Builds the quantized palette from the given image frame and bounds.
+        /// Adds colors to the quantized palette from the given pixel source.
         /// </summary>
-        /// <param name="source">The source image frame.</param>
-        /// <param name="bounds">The region of interest bounds.</param>
-        void BuildPalette(ImageFrame<TPixel> source, Rectangle bounds);
+        /// <param name="pixelRegion">The <see cref="BufferRegion{T}"/> of source pixels to register.</param>
+        void CollectPaletteColors(BufferRegion<TPixel> pixelRegion);
 
         /// <summary>
         /// Quantizes an image frame and return the resulting output pixels.
diff --git a/src/ImageSharp/Processing/Processors/Quantization/IQuantizer.cs b/src/ImageSharp/Processing/Processors/Quantization/IQuantizer.cs
index 01e4b5e8a..e59b9a6a7 100644
--- a/src/ImageSharp/Processing/Processors/Quantization/IQuantizer.cs
+++ b/src/ImageSharp/Processing/Processors/Quantization/IQuantizer.cs
@@ -20,8 +20,8 @@ namespace SixLabors.ImageSharp.Processing.Processors.Quantization
         /// </summary>
         /// <param name="configuration">The <see cref="Configuration"/> to configure internal operations.</param>
         /// <typeparam name="TPixel">The pixel format.</typeparam>
-        /// <returns>The <see cref="IFrameQuantizer{TPixel}"/>.</returns>
-        IFrameQuantizer<TPixel> CreateFrameQuantizer<TPixel>(Configuration configuration)
+        /// <returns>The <see cref="IQuantizer{TPixel}"/>.</returns>
+        IQuantizer<TPixel> CreatePixelSpecificQuantizer<TPixel>(Configuration configuration)
             where TPixel : unmanaged, IPixel<TPixel>;
 
         /// <summary>
@@ -30,8 +30,8 @@ namespace SixLabors.ImageSharp.Processing.Processors.Quantization
         /// <typeparam name="TPixel">The pixel format.</typeparam>
         /// <param name="configuration">The <see cref="Configuration"/> to configure internal operations.</param>
         /// <param name="options">The options to create the quantizer with.</param>
-        /// <returns>The <see cref="IFrameQuantizer{TPixel}"/>.</returns>
-        IFrameQuantizer<TPixel> CreateFrameQuantizer<TPixel>(Configuration configuration, QuantizerOptions options)
+        /// <returns>The <see cref="IQuantizer{TPixel}"/>.</returns>
+        IQuantizer<TPixel> CreatePixelSpecificQuantizer<TPixel>(Configuration configuration, QuantizerOptions options)
             where TPixel : unmanaged, IPixel<TPixel>;
     }
 }
diff --git a/src/ImageSharp/Processing/Processors/Quantization/OctreeQuantizer.cs b/src/ImageSharp/Processing/Processors/Quantization/OctreeQuantizer.cs
index 9e04edef0..02e85167d 100644
--- a/src/ImageSharp/Processing/Processors/Quantization/OctreeQuantizer.cs
+++ b/src/ImageSharp/Processing/Processors/Quantization/OctreeQuantizer.cs
@@ -36,13 +36,13 @@ namespace SixLabors.ImageSharp.Processing.Processors.Quantization
         public QuantizerOptions Options { get; }
 
         /// <inheritdoc />
-        public IFrameQuantizer<TPixel> CreateFrameQuantizer<TPixel>(Configuration configuration)
+        public IQuantizer<TPixel> CreatePixelSpecificQuantizer<TPixel>(Configuration configuration)
             where TPixel : unmanaged, IPixel<TPixel>
-            => this.CreateFrameQuantizer<TPixel>(configuration, this.Options);
+            => this.CreatePixelSpecificQuantizer<TPixel>(configuration, this.Options);
 
         /// <inheritdoc />
-        public IFrameQuantizer<TPixel> CreateFrameQuantizer<TPixel>(Configuration configuration, QuantizerOptions options)
+        public IQuantizer<TPixel> CreatePixelSpecificQuantizer<TPixel>(Configuration configuration, QuantizerOptions options)
             where TPixel : unmanaged, IPixel<TPixel>
-            => new OctreeFrameQuantizer<TPixel>(configuration, options);
+            => new OctreeQuantizer<TPixel>(configuration, options);
     }
 }
diff --git a/src/ImageSharp/Processing/Processors/Quantization/OctreeFrameQuantizer{TPixel}.cs b/src/ImageSharp/Processing/Processors/Quantization/OctreeQuantizer{TPixel}.cs
similarity index 97%
rename from src/ImageSharp/Processing/Processors/Quantization/OctreeFrameQuantizer{TPixel}.cs
rename to src/ImageSharp/Processing/Processors/Quantization/OctreeQuantizer{TPixel}.cs
index ce2e406d4..2a9b8d79b 100644
--- a/src/ImageSharp/Processing/Processors/Quantization/OctreeFrameQuantizer{TPixel}.cs
+++ b/src/ImageSharp/Processing/Processors/Quantization/OctreeQuantizer{TPixel}.cs
@@ -17,7 +17,7 @@ namespace SixLabors.ImageSharp.Processing.Processors.Quantization
     /// <see href="http://msdn.microsoft.com/en-us/library/aa479306.aspx"/>
     /// </summary>
     /// <typeparam name="TPixel">The pixel format.</typeparam>
-    public struct OctreeFrameQuantizer<TPixel> : IFrameQuantizer<TPixel>
+    public struct OctreeQuantizer<TPixel> : IQuantizer<TPixel>
         where TPixel : unmanaged, IPixel<TPixel>
     {
         private readonly int maxColors;
@@ -29,12 +29,12 @@ namespace SixLabors.ImageSharp.Processing.Processors.Quantization
         private bool isDisposed;
 
         /// <summary>
-        /// Initializes a new instance of the <see cref="OctreeFrameQuantizer{TPixel}"/> struct.
+        /// Initializes a new instance of the <see cref="OctreeQuantizer{TPixel}"/> struct.
         /// </summary>
         /// <param name="configuration">The configuration which allows altering default behaviour or extending the library.</param>
         /// <param name="options">The quantizer options defining quantization rules.</param>
         [MethodImpl(InliningOptions.ShortMethod)]
-        public OctreeFrameQuantizer(Configuration configuration, QuantizerOptions options)
+        public OctreeQuantizer(Configuration configuration, QuantizerOptions options)
         {
             Guard.NotNull(configuration, nameof(configuration));
             Guard.NotNull(options, nameof(options));
@@ -69,15 +69,17 @@ namespace SixLabors.ImageSharp.Processing.Processors.Quantization
 
         /// <inheritdoc/>
         [MethodImpl(InliningOptions.ShortMethod)]
-        public void BuildPalette(ImageFrame<TPixel> source, Rectangle bounds)
+        public void CollectPaletteColors(BufferRegion<TPixel> pixelRegion)
         {
+            Rectangle bounds = pixelRegion.Rectangle;
+            Buffer2D<TPixel> source = pixelRegion.Buffer;
             using IMemoryOwner<Rgba32> buffer = this.Configuration.MemoryAllocator.Allocate<Rgba32>(bounds.Width);
             Span<Rgba32> bufferSpan = buffer.GetSpan();
 
             // Loop through each row
             for (int y = bounds.Top; y < bounds.Bottom; y++)
             {
-                Span<TPixel> row = source.GetPixelRowSpan(y).Slice(bounds.Left, bounds.Width);
+                Span<TPixel> row = source.GetRowSpan(y).Slice(bounds.Left, bounds.Width);
                 PixelOperations<TPixel>.Instance.ToRgba32(this.Configuration, row, bufferSpan);
 
                 for (int x = 0; x < bufferSpan.Length; x++)
diff --git a/src/ImageSharp/Processing/Processors/Quantization/PaletteQuantizer.cs b/src/ImageSharp/Processing/Processors/Quantization/PaletteQuantizer.cs
index c14ea6153..38816a168 100644
--- a/src/ImageSharp/Processing/Processors/Quantization/PaletteQuantizer.cs
+++ b/src/ImageSharp/Processing/Processors/Quantization/PaletteQuantizer.cs
@@ -41,12 +41,12 @@ namespace SixLabors.ImageSharp.Processing.Processors.Quantization
         public QuantizerOptions Options { get; }
 
         /// <inheritdoc />
-        public IFrameQuantizer<TPixel> CreateFrameQuantizer<TPixel>(Configuration configuration)
+        public IQuantizer<TPixel> CreatePixelSpecificQuantizer<TPixel>(Configuration configuration)
             where TPixel : unmanaged, IPixel<TPixel>
-            => this.CreateFrameQuantizer<TPixel>(configuration, this.Options);
+            => this.CreatePixelSpecificQuantizer<TPixel>(configuration, this.Options);
 
         /// <inheritdoc />
-        public IFrameQuantizer<TPixel> CreateFrameQuantizer<TPixel>(Configuration configuration, QuantizerOptions options)
+        public IQuantizer<TPixel> CreatePixelSpecificQuantizer<TPixel>(Configuration configuration, QuantizerOptions options)
             where TPixel : unmanaged, IPixel<TPixel>
         {
             Guard.NotNull(options, nameof(options));
@@ -60,7 +60,7 @@ namespace SixLabors.ImageSharp.Processing.Processors.Quantization
             Color.ToPixel(configuration, this.colorPalette.Span, palette.AsSpan());
 
             var pixelMap = new EuclideanPixelMap<TPixel>(configuration, palette);
-            return new PaletteFrameQuantizer<TPixel>(configuration, options, pixelMap);
+            return new PaletteQuantizer<TPixel>(configuration, options, pixelMap);
         }
     }
 }
diff --git a/src/ImageSharp/Processing/Processors/Quantization/PaletteFrameQuantizer{TPixel}.cs b/src/ImageSharp/Processing/Processors/Quantization/PaletteQuantizer{TPixel}.cs
similarity index 91%
rename from src/ImageSharp/Processing/Processors/Quantization/PaletteFrameQuantizer{TPixel}.cs
rename to src/ImageSharp/Processing/Processors/Quantization/PaletteQuantizer{TPixel}.cs
index ade73e2d0..e40cf0c8c 100644
--- a/src/ImageSharp/Processing/Processors/Quantization/PaletteFrameQuantizer{TPixel}.cs
+++ b/src/ImageSharp/Processing/Processors/Quantization/PaletteQuantizer{TPixel}.cs
@@ -3,6 +3,7 @@
 
 using System;
 using System.Runtime.CompilerServices;
+using SixLabors.ImageSharp.Memory;
 using SixLabors.ImageSharp.PixelFormats;
 
 namespace SixLabors.ImageSharp.Processing.Processors.Quantization
@@ -12,19 +13,19 @@ namespace SixLabors.ImageSharp.Processing.Processors.Quantization
     /// <see href="http://msdn.microsoft.com/en-us/library/aa479306.aspx"/>
     /// </summary>
     /// <typeparam name="TPixel">The pixel format.</typeparam>
-    internal struct PaletteFrameQuantizer<TPixel> : IFrameQuantizer<TPixel>
+    internal struct PaletteQuantizer<TPixel> : IQuantizer<TPixel>
         where TPixel : unmanaged, IPixel<TPixel>
     {
         private readonly EuclideanPixelMap<TPixel> pixelMap;
 
         /// <summary>
-        /// Initializes a new instance of the <see cref="PaletteFrameQuantizer{TPixel}"/> struct.
+        /// Initializes a new instance of the <see cref="PaletteQuantizer{TPixel}"/> struct.
         /// </summary>
         /// <param name="configuration">The configuration which allows altering default behaviour or extending the library.</param>
         /// <param name="options">The quantizer options defining quantization rules.</param>
         /// <param name="pixelMap">The pixel map for looking up color matches from a predefined palette.</param>
         [MethodImpl(InliningOptions.ShortMethod)]
-        public PaletteFrameQuantizer(
+        public PaletteQuantizer(
             Configuration configuration,
             QuantizerOptions options,
             EuclideanPixelMap<TPixel> pixelMap)
@@ -53,7 +54,7 @@ namespace SixLabors.ImageSharp.Processing.Processors.Quantization
 
         /// <inheritdoc/>
         [MethodImpl(InliningOptions.ShortMethod)]
-        public void BuildPalette(ImageFrame<TPixel> source, Rectangle bounds)
+        public void CollectPaletteColors(BufferRegion<TPixel> pixelRegion)
         {
         }
 
diff --git a/src/ImageSharp/Processing/Processors/Quantization/QuantizeProcessor{TPixel}.cs b/src/ImageSharp/Processing/Processors/Quantization/QuantizeProcessor{TPixel}.cs
index 386caf1be..dce769692 100644
--- a/src/ImageSharp/Processing/Processors/Quantization/QuantizeProcessor{TPixel}.cs
+++ b/src/ImageSharp/Processing/Processors/Quantization/QuantizeProcessor{TPixel}.cs
@@ -38,7 +38,7 @@ namespace SixLabors.ImageSharp.Processing.Processors.Quantization
             var interest = Rectangle.Intersect(source.Bounds(), this.SourceRectangle);
 
             Configuration configuration = this.Configuration;
-            using IFrameQuantizer<TPixel> frameQuantizer = this.quantizer.CreateFrameQuantizer<TPixel>(configuration);
+            using IQuantizer<TPixel> frameQuantizer = this.quantizer.CreatePixelSpecificQuantizer<TPixel>(configuration);
             using IndexedImageFrame<TPixel> quantized = frameQuantizer.QuantizeFrame(source, interest);
 
             var operation = new RowIntervalOperation(this.SourceRectangle, source, quantized);
diff --git a/src/ImageSharp/Processing/Processors/Quantization/WuQuantizer.cs b/src/ImageSharp/Processing/Processors/Quantization/WuQuantizer.cs
index d2e33aa1f..0f1dff181 100644
--- a/src/ImageSharp/Processing/Processors/Quantization/WuQuantizer.cs
+++ b/src/ImageSharp/Processing/Processors/Quantization/WuQuantizer.cs
@@ -35,13 +35,13 @@ namespace SixLabors.ImageSharp.Processing.Processors.Quantization
         public QuantizerOptions Options { get; }
 
         /// <inheritdoc />
-        public IFrameQuantizer<TPixel> CreateFrameQuantizer<TPixel>(Configuration configuration)
+        public IQuantizer<TPixel> CreatePixelSpecificQuantizer<TPixel>(Configuration configuration)
             where TPixel : unmanaged, IPixel<TPixel>
-            => this.CreateFrameQuantizer<TPixel>(configuration, this.Options);
+            => this.CreatePixelSpecificQuantizer<TPixel>(configuration, this.Options);
 
         /// <inheritdoc />
-        public IFrameQuantizer<TPixel> CreateFrameQuantizer<TPixel>(Configuration configuration, QuantizerOptions options)
+        public IQuantizer<TPixel> CreatePixelSpecificQuantizer<TPixel>(Configuration configuration, QuantizerOptions options)
             where TPixel : unmanaged, IPixel<TPixel>
-            => new WuFrameQuantizer<TPixel>(configuration, options);
+            => new WuQuantizer<TPixel>(configuration, options);
     }
 }
diff --git a/src/ImageSharp/Processing/Processors/Quantization/WuFrameQuantizer{TPixel}.cs b/src/ImageSharp/Processing/Processors/Quantization/WuQuantizer{TPixel}.cs
similarity index 98%
rename from src/ImageSharp/Processing/Processors/Quantization/WuFrameQuantizer{TPixel}.cs
rename to src/ImageSharp/Processing/Processors/Quantization/WuQuantizer{TPixel}.cs
index d15db74e6..a83bf3b6d 100644
--- a/src/ImageSharp/Processing/Processors/Quantization/WuFrameQuantizer{TPixel}.cs
+++ b/src/ImageSharp/Processing/Processors/Quantization/WuQuantizer{TPixel}.cs
@@ -32,7 +32,7 @@ namespace SixLabors.ImageSharp.Processing.Processors.Quantization
     /// </para>
     /// </remarks>
     /// <typeparam name="TPixel">The pixel format.</typeparam>
-    internal struct WuFrameQuantizer<TPixel> : IFrameQuantizer<TPixel>
+    internal struct WuQuantizer<TPixel> : IQuantizer<TPixel>
         where TPixel : unmanaged, IPixel<TPixel>
     {
         private readonly MemoryAllocator memoryAllocator;
@@ -77,12 +77,12 @@ namespace SixLabors.ImageSharp.Processing.Processors.Quantization
         private bool isDisposed;
 
         /// <summary>
-        /// Initializes a new instance of the <see cref="WuFrameQuantizer{TPixel}"/> struct.
+        /// Initializes a new instance of the <see cref="WuQuantizer{TPixel}"/> struct.
         /// </summary>
         /// <param name="configuration">The configuration which allows altering default behaviour or extending the library.</param>
         /// <param name="options">The quantizer options defining quantization rules.</param>
         [MethodImpl(InliningOptions.ShortMethod)]
-        public WuFrameQuantizer(Configuration configuration, QuantizerOptions options)
+        public WuQuantizer(Configuration configuration, QuantizerOptions options)
         {
             Guard.NotNull(configuration, nameof(configuration));
             Guard.NotNull(options, nameof(options));
@@ -118,8 +118,11 @@ namespace SixLabors.ImageSharp.Processing.Processors.Quantization
         }
 
         /// <inheritdoc/>
-        public void BuildPalette(ImageFrame<TPixel> source, Rectangle bounds)
+        public void CollectPaletteColors(BufferRegion<TPixel> pixelRegion)
         {
+            Rectangle bounds = pixelRegion.Rectangle;
+            Buffer2D<TPixel> source = pixelRegion.Buffer;
+
             this.Build3DHistogram(source, bounds);
             this.Get3DMoments(this.memoryAllocator);
             this.BuildCube();
@@ -360,7 +363,7 @@ namespace SixLabors.ImageSharp.Processing.Processors.Quantization
         /// </summary>
         /// <param name="source">The source data.</param>
         /// <param name="bounds">The bounds within the source image to quantize.</param>
-        private void Build3DHistogram(ImageFrame<TPixel> source, Rectangle bounds)
+        private void Build3DHistogram(Buffer2D<TPixel> source, Rectangle bounds)
         {
             Span<Moment> momentSpan = this.momentsOwner.GetSpan();
 
@@ -370,7 +373,7 @@ namespace SixLabors.ImageSharp.Processing.Processors.Quantization
 
             for (int y = bounds.Top; y < bounds.Bottom; y++)
             {
-                Span<TPixel> row = source.GetPixelRowSpan(y).Slice(bounds.Left, bounds.Width);
+                Span<TPixel> row = source.GetRowSpan(y).Slice(bounds.Left, bounds.Width);
                 PixelOperations<TPixel>.Instance.ToRgba32(this.Configuration, row, bufferSpan);
 
                 for (int x = 0; x < bufferSpan.Length; x++)
diff --git a/tests/ImageSharp.Tests/Processing/Processors/Quantization/OctreeQuantizerTests.cs b/tests/ImageSharp.Tests/Processing/Processors/Quantization/OctreeQuantizerTests.cs
index bb7921d68..dd27164f3 100644
--- a/tests/ImageSharp.Tests/Processing/Processors/Quantization/OctreeQuantizerTests.cs
+++ b/tests/ImageSharp.Tests/Processing/Processors/Quantization/OctreeQuantizerTests.cs
@@ -39,7 +39,7 @@ namespace SixLabors.ImageSharp.Tests.Processing.Processors.Quantization
         public void OctreeQuantizerCanCreateFrameQuantizer()
         {
             var quantizer = new OctreeQuantizer();
-            IFrameQuantizer<Rgba32> frameQuantizer = quantizer.CreateFrameQuantizer<Rgba32>(Configuration.Default);
+            IQuantizer<Rgba32> frameQuantizer = quantizer.CreatePixelSpecificQuantizer<Rgba32>(Configuration.Default);
 
             Assert.NotNull(frameQuantizer);
             Assert.NotNull(frameQuantizer.Options);
@@ -47,14 +47,14 @@ namespace SixLabors.ImageSharp.Tests.Processing.Processors.Quantization
             frameQuantizer.Dispose();
 
             quantizer = new OctreeQuantizer(new QuantizerOptions { Dither = null });
-            frameQuantizer = quantizer.CreateFrameQuantizer<Rgba32>(Configuration.Default);
+            frameQuantizer = quantizer.CreatePixelSpecificQuantizer<Rgba32>(Configuration.Default);
 
             Assert.NotNull(frameQuantizer);
             Assert.Null(frameQuantizer.Options.Dither);
             frameQuantizer.Dispose();
 
             quantizer = new OctreeQuantizer(new QuantizerOptions { Dither = KnownDitherings.Atkinson });
-            frameQuantizer = quantizer.CreateFrameQuantizer<Rgba32>(Configuration.Default);
+            frameQuantizer = quantizer.CreatePixelSpecificQuantizer<Rgba32>(Configuration.Default);
             Assert.NotNull(frameQuantizer);
             Assert.Equal(KnownDitherings.Atkinson, frameQuantizer.Options.Dither);
             frameQuantizer.Dispose();
diff --git a/tests/ImageSharp.Tests/Processing/Processors/Quantization/PaletteQuantizerTests.cs b/tests/ImageSharp.Tests/Processing/Processors/Quantization/PaletteQuantizerTests.cs
index 3c1fa11ab..acc9a0e01 100644
--- a/tests/ImageSharp.Tests/Processing/Processors/Quantization/PaletteQuantizerTests.cs
+++ b/tests/ImageSharp.Tests/Processing/Processors/Quantization/PaletteQuantizerTests.cs
@@ -41,7 +41,7 @@ namespace SixLabors.ImageSharp.Tests.Processing.Processors.Quantization
         public void PaletteQuantizerCanCreateFrameQuantizer()
         {
             var quantizer = new PaletteQuantizer(Palette);
-            IFrameQuantizer<Rgba32> frameQuantizer = quantizer.CreateFrameQuantizer<Rgba32>(Configuration.Default);
+            IQuantizer<Rgba32> frameQuantizer = quantizer.CreatePixelSpecificQuantizer<Rgba32>(Configuration.Default);
 
             Assert.NotNull(frameQuantizer);
             Assert.NotNull(frameQuantizer.Options);
@@ -49,14 +49,14 @@ namespace SixLabors.ImageSharp.Tests.Processing.Processors.Quantization
             frameQuantizer.Dispose();
 
             quantizer = new PaletteQuantizer(Palette, new QuantizerOptions { Dither = null });
-            frameQuantizer = quantizer.CreateFrameQuantizer<Rgba32>(Configuration.Default);
+            frameQuantizer = quantizer.CreatePixelSpecificQuantizer<Rgba32>(Configuration.Default);
 
             Assert.NotNull(frameQuantizer);
             Assert.Null(frameQuantizer.Options.Dither);
             frameQuantizer.Dispose();
 
             quantizer = new PaletteQuantizer(Palette, new QuantizerOptions { Dither = KnownDitherings.Atkinson });
-            frameQuantizer = quantizer.CreateFrameQuantizer<Rgba32>(Configuration.Default);
+            frameQuantizer = quantizer.CreatePixelSpecificQuantizer<Rgba32>(Configuration.Default);
             Assert.NotNull(frameQuantizer);
             Assert.Equal(KnownDitherings.Atkinson, frameQuantizer.Options.Dither);
             frameQuantizer.Dispose();
diff --git a/tests/ImageSharp.Tests/Processing/Processors/Quantization/WuQuantizerTests.cs b/tests/ImageSharp.Tests/Processing/Processors/Quantization/WuQuantizerTests.cs
index eb9d738e9..d78e9254c 100644
--- a/tests/ImageSharp.Tests/Processing/Processors/Quantization/WuQuantizerTests.cs
+++ b/tests/ImageSharp.Tests/Processing/Processors/Quantization/WuQuantizerTests.cs
@@ -39,7 +39,7 @@ namespace SixLabors.ImageSharp.Tests.Processing.Processors.Quantization
         public void WuQuantizerCanCreateFrameQuantizer()
         {
             var quantizer = new WuQuantizer();
-            IFrameQuantizer<Rgba32> frameQuantizer = quantizer.CreateFrameQuantizer<Rgba32>(Configuration.Default);
+            IQuantizer<Rgba32> frameQuantizer = quantizer.CreatePixelSpecificQuantizer<Rgba32>(Configuration.Default);
 
             Assert.NotNull(frameQuantizer);
             Assert.NotNull(frameQuantizer.Options);
@@ -47,14 +47,14 @@ namespace SixLabors.ImageSharp.Tests.Processing.Processors.Quantization
             frameQuantizer.Dispose();
 
             quantizer = new WuQuantizer(new QuantizerOptions { Dither = null });
-            frameQuantizer = quantizer.CreateFrameQuantizer<Rgba32>(Configuration.Default);
+            frameQuantizer = quantizer.CreatePixelSpecificQuantizer<Rgba32>(Configuration.Default);
 
             Assert.NotNull(frameQuantizer);
             Assert.Null(frameQuantizer.Options.Dither);
             frameQuantizer.Dispose();
 
             quantizer = new WuQuantizer(new QuantizerOptions { Dither = KnownDitherings.Atkinson });
-            frameQuantizer = quantizer.CreateFrameQuantizer<Rgba32>(Configuration.Default);
+            frameQuantizer = quantizer.CreatePixelSpecificQuantizer<Rgba32>(Configuration.Default);
             Assert.NotNull(frameQuantizer);
             Assert.Equal(KnownDitherings.Atkinson, frameQuantizer.Options.Dither);
             frameQuantizer.Dispose();
diff --git a/tests/ImageSharp.Tests/Quantization/QuantizedImageTests.cs b/tests/ImageSharp.Tests/Quantization/QuantizedImageTests.cs
index 7945741b0..86229a7b6 100644
--- a/tests/ImageSharp.Tests/Quantization/QuantizedImageTests.cs
+++ b/tests/ImageSharp.Tests/Quantization/QuantizedImageTests.cs
@@ -27,22 +27,22 @@ namespace SixLabors.ImageSharp.Tests
             Assert.NotNull(octree.Options.Dither);
             Assert.NotNull(wu.Options.Dither);
 
-            using (IFrameQuantizer<Rgba32> quantizer = werner.CreateFrameQuantizer<Rgba32>(this.Configuration))
+            using (IQuantizer<Rgba32> quantizer = werner.CreatePixelSpecificQuantizer<Rgba32>(this.Configuration))
             {
                 Assert.NotNull(quantizer.Options.Dither);
             }
 
-            using (IFrameQuantizer<Rgba32> quantizer = webSafe.CreateFrameQuantizer<Rgba32>(this.Configuration))
+            using (IQuantizer<Rgba32> quantizer = webSafe.CreatePixelSpecificQuantizer<Rgba32>(this.Configuration))
             {
                 Assert.NotNull(quantizer.Options.Dither);
             }
 
-            using (IFrameQuantizer<Rgba32> quantizer = octree.CreateFrameQuantizer<Rgba32>(this.Configuration))
+            using (IQuantizer<Rgba32> quantizer = octree.CreatePixelSpecificQuantizer<Rgba32>(this.Configuration))
             {
                 Assert.NotNull(quantizer.Options.Dither);
             }
 
-            using (IFrameQuantizer<Rgba32> quantizer = wu.CreateFrameQuantizer<Rgba32>(this.Configuration))
+            using (IQuantizer<Rgba32> quantizer = wu.CreatePixelSpecificQuantizer<Rgba32>(this.Configuration))
             {
                 Assert.NotNull(quantizer.Options.Dither);
             }
@@ -70,7 +70,7 @@ namespace SixLabors.ImageSharp.Tests
 
                 foreach (ImageFrame<TPixel> frame in image.Frames)
                 {
-                    using (IFrameQuantizer<TPixel> frameQuantizer = quantizer.CreateFrameQuantizer<TPixel>(this.Configuration))
+                    using (IQuantizer<TPixel> frameQuantizer = quantizer.CreatePixelSpecificQuantizer<TPixel>(this.Configuration))
                     using (IndexedImageFrame<TPixel> quantized = frameQuantizer.QuantizeFrame(frame, frame.Bounds()))
                     {
                         int index = this.GetTransparentIndex(quantized);
@@ -100,7 +100,7 @@ namespace SixLabors.ImageSharp.Tests
 
                 foreach (ImageFrame<TPixel> frame in image.Frames)
                 {
-                    using (IFrameQuantizer<TPixel> frameQuantizer = quantizer.CreateFrameQuantizer<TPixel>(this.Configuration))
+                    using (IQuantizer<TPixel> frameQuantizer = quantizer.CreatePixelSpecificQuantizer<TPixel>(this.Configuration))
                     using (IndexedImageFrame<TPixel> quantized = frameQuantizer.QuantizeFrame(frame, frame.Bounds()))
                     {
                         int index = this.GetTransparentIndex(quantized);
diff --git a/tests/ImageSharp.Tests/Quantization/WuQuantizerTests.cs b/tests/ImageSharp.Tests/Quantization/WuQuantizerTests.cs
index 37b8cab60..75e88ba79 100644
--- a/tests/ImageSharp.Tests/Quantization/WuQuantizerTests.cs
+++ b/tests/ImageSharp.Tests/Quantization/WuQuantizerTests.cs
@@ -20,7 +20,7 @@ namespace SixLabors.ImageSharp.Tests.Quantization
             using var image = new Image<Rgba32>(config, 1, 1, Color.Black);
             ImageFrame<Rgba32> frame = image.Frames.RootFrame;
 
-            using IFrameQuantizer<Rgba32> frameQuantizer = quantizer.CreateFrameQuantizer<Rgba32>(config);
+            using IQuantizer<Rgba32> frameQuantizer = quantizer.CreatePixelSpecificQuantizer<Rgba32>(config);
             using IndexedImageFrame<Rgba32> result = frameQuantizer.QuantizeFrame(frame, frame.Bounds());
 
             Assert.Equal(1, result.Palette.Length);
@@ -40,7 +40,7 @@ namespace SixLabors.ImageSharp.Tests.Quantization
             using var image = new Image<Rgba32>(config, 1, 1, default(Rgba32));
             ImageFrame<Rgba32> frame = image.Frames.RootFrame;
 
-            using IFrameQuantizer<Rgba32> frameQuantizer = quantizer.CreateFrameQuantizer<Rgba32>(config);
+            using IQuantizer<Rgba32> frameQuantizer = quantizer.CreatePixelSpecificQuantizer<Rgba32>(config);
             using IndexedImageFrame<Rgba32> result = frameQuantizer.QuantizeFrame(frame, frame.Bounds());
 
             Assert.Equal(1, result.Palette.Length);
@@ -86,7 +86,7 @@ namespace SixLabors.ImageSharp.Tests.Quantization
 
             ImageFrame<Rgba32> frame = image.Frames.RootFrame;
 
-            using IFrameQuantizer<Rgba32> frameQuantizer = quantizer.CreateFrameQuantizer<Rgba32>(config);
+            using IQuantizer<Rgba32> frameQuantizer = quantizer.CreatePixelSpecificQuantizer<Rgba32>(config);
             using IndexedImageFrame<Rgba32> result = frameQuantizer.QuantizeFrame(frame, frame.Bounds());
 
             Assert.Equal(256, result.Palette.Length);
@@ -126,7 +126,7 @@ namespace SixLabors.ImageSharp.Tests.Quantization
                 var quantizer = new WuQuantizer(new QuantizerOptions { Dither = null });
                 ImageFrame<TPixel> frame = image.Frames.RootFrame;
 
-                using IFrameQuantizer<TPixel> frameQuantizer = quantizer.CreateFrameQuantizer<TPixel>(config);
+                using IQuantizer<TPixel> frameQuantizer = quantizer.CreatePixelSpecificQuantizer<TPixel>(config);
                 using IndexedImageFrame<TPixel> result = frameQuantizer.QuantizeFrame(frame, frame.Bounds());
 
                 Assert.Equal(48, result.Palette.Length);
@@ -155,7 +155,7 @@ namespace SixLabors.ImageSharp.Tests.Quantization
                 var quantizer = new WuQuantizer(new QuantizerOptions { Dither = null });
 
                 ImageFrame<Rgba32> frame = image.Frames.RootFrame;
-                using (IFrameQuantizer<Rgba32> frameQuantizer = quantizer.CreateFrameQuantizer<Rgba32>(config))
+                using (IQuantizer<Rgba32> frameQuantizer = quantizer.CreatePixelSpecificQuantizer<Rgba32>(config))
                 using (IndexedImageFrame<Rgba32> result = frameQuantizer.QuantizeFrame(frame, frame.Bounds()))
                 {
                     Assert.Equal(4 * 8, result.Palette.Length);