diff --git a/framework/src/Volo.Abp.EntityFrameworkCore.MySQL/Volo/Abp/EntityFrameworkCore/AbpDbContextConfigurationContextMySQLExtensions.cs b/framework/src/Volo.Abp.EntityFrameworkCore.MySQL/Volo/Abp/EntityFrameworkCore/AbpDbContextConfigurationContextMySQLExtensions.cs
index f04f8fd4f3..2ec3383ddc 100644
--- a/framework/src/Volo.Abp.EntityFrameworkCore.MySQL/Volo/Abp/EntityFrameworkCore/AbpDbContextConfigurationContextMySQLExtensions.cs
+++ b/framework/src/Volo.Abp.EntityFrameworkCore.MySQL/Volo/Abp/EntityFrameworkCore/AbpDbContextConfigurationContextMySQLExtensions.cs
@@ -1,7 +1,9 @@
 using JetBrains.Annotations;
 using Microsoft.EntityFrameworkCore;
+using Microsoft.EntityFrameworkCore.Infrastructure;
 using System;
 using Volo.Abp.EntityFrameworkCore.DependencyInjection;
+using Volo.Abp.EntityFrameworkCore.MySQL;
 
 namespace Volo.Abp.EntityFrameworkCore;
 
@@ -11,21 +13,21 @@ public static class AbpDbContextConfigurationContextMySQLExtensions
         [NotNull] this AbpDbContextConfigurationContext context,
         Action<MySql.EntityFrameworkCore.Infrastructure.MySQLDbContextOptionsBuilder>? mySQLOptionsAction = null)
     {
-        if (context.ExistingConnection != null)
-        {
-            return context.DbContextOptions.UseMySQL(context.ExistingConnection, optionsBuilder =>
+        var dbContextOptionsBuilder = context.ExistingConnection != null
+            ? context.DbContextOptions.UseMySQL(context.ExistingConnection, optionsBuilder =>
             {
                 optionsBuilder.UseQuerySplittingBehavior(QuerySplittingBehavior.SplitQuery);
                 mySQLOptionsAction?.Invoke(optionsBuilder);
-            });
-        }
-        else
-        {
-            return context.DbContextOptions.UseMySQL(context.ConnectionString, optionsBuilder =>
+            })
+            : context.DbContextOptions.UseMySQL(context.ConnectionString, optionsBuilder =>
             {
                 optionsBuilder.UseQuerySplittingBehavior(QuerySplittingBehavior.SplitQuery);
                 mySQLOptionsAction?.Invoke(optionsBuilder);
             });
-        }
+
+        ((IDbContextOptionsBuilderInfrastructure)dbContextOptionsBuilder)
+            .AddOrUpdateExtension(new AbpMySQLDbContextOptionsExtension());
+
+        return dbContextOptionsBuilder;
     }
 }
diff --git a/framework/src/Volo.Abp.EntityFrameworkCore.MySQL/Volo/Abp/EntityFrameworkCore/MySQL/AbpMySQLDbContextOptionsExtension.cs b/framework/src/Volo.Abp.EntityFrameworkCore.MySQL/Volo/Abp/EntityFrameworkCore/MySQL/AbpMySQLDbContextOptionsExtension.cs
new file mode 100644
index 0000000000..bea4ed8432
--- /dev/null
+++ b/framework/src/Volo.Abp.EntityFrameworkCore.MySQL/Volo/Abp/EntityFrameworkCore/MySQL/AbpMySQLDbContextOptionsExtension.cs
@@ -0,0 +1,48 @@
+using System.Collections.Generic;
+using Microsoft.EntityFrameworkCore.Infrastructure;
+using Microsoft.EntityFrameworkCore.Storage;
+using Microsoft.Extensions.DependencyInjection;
+using Microsoft.Extensions.DependencyInjection.Extensions;
+
+namespace Volo.Abp.EntityFrameworkCore.MySQL;
+
+/* Registers ABP services into the EF Core internal service provider to patch
+ * MySQL provider issues (currently the Guid[] type mapping plugin). */
+internal sealed class AbpMySQLDbContextOptionsExtension : IDbContextOptionsExtension
+{
+    public DbContextOptionsExtensionInfo Info => new ExtensionInfo(this);
+
+    public void ApplyServices(IServiceCollection services)
+    {
+        services.TryAddEnumerable(
+            ServiceDescriptor.Singleton<IRelationalTypeMappingSourcePlugin, MySQLGuidArrayTypeMappingSourcePlugin>());
+    }
+
+    public void Validate(IDbContextOptions options)
+    {
+    }
+
+    private sealed class ExtensionInfo : DbContextOptionsExtensionInfo
+    {
+        public ExtensionInfo(IDbContextOptionsExtension extension)
+            : base(extension)
+        {
+        }
+
+        public override bool IsDatabaseProvider => false;
+
+        public override string LogFragment => "using AbpMySQL ";
+
+        public override int GetServiceProviderHashCode() => 0;
+
+        public override bool ShouldUseSameServiceProvider(DbContextOptionsExtensionInfo other)
+        {
+            return other is ExtensionInfo;
+        }
+
+        public override void PopulateDebugInfo(IDictionary<string, string> debugInfo)
+        {
+            debugInfo["Volo.Abp.EntityFrameworkCore.MySQL"] = "1";
+        }
+    }
+}
diff --git a/framework/src/Volo.Abp.EntityFrameworkCore.MySQL/Volo/Abp/EntityFrameworkCore/MySQL/MySQLGuidArrayTypeMappingSourcePlugin.cs b/framework/src/Volo.Abp.EntityFrameworkCore.MySQL/Volo/Abp/EntityFrameworkCore/MySQL/MySQLGuidArrayTypeMappingSourcePlugin.cs
new file mode 100644
index 0000000000..e3ac23563c
--- /dev/null
+++ b/framework/src/Volo.Abp.EntityFrameworkCore.MySQL/Volo/Abp/EntityFrameworkCore/MySQL/MySQLGuidArrayTypeMappingSourcePlugin.cs
@@ -0,0 +1,25 @@
+using System;
+using System.Data;
+using Microsoft.EntityFrameworkCore.Storage;
+
+namespace Volo.Abp.EntityFrameworkCore.MySQL;
+
+/* MySql.EntityFrameworkCore (up to 10.0.9) maps Guid[] query parameters to its
+ * scalar GUID mapping and throws NullReferenceException at parameter binding.
+ * This plugin runs before the provider's own lookup and returns the collection
+ * mapping the provider already builds for List<Guid>. Remove once the provider
+ * handles Guid[] parameters. */
+internal sealed class MySQLGuidArrayTypeMappingSourcePlugin : IRelationalTypeMappingSourcePlugin
+{
+    public RelationalTypeMapping? FindMapping(in RelationalTypeMappingInfo mappingInfo)
+    {
+        if (mappingInfo.ClrType == typeof(Guid[]) && mappingInfo.ElementTypeMapping is not null)
+        {
+            return new StringTypeMapping("longtext", DbType.String).Clone(
+                clrType: typeof(Guid[]),
+                elementMapping: mappingInfo.ElementTypeMapping);
+        }
+
+        return null;
+    }
+}
diff --git a/framework/test/Volo.Abp.EntityFrameworkCore.Tests/Volo.Abp.EntityFrameworkCore.Tests.csproj b/framework/test/Volo.Abp.EntityFrameworkCore.Tests/Volo.Abp.EntityFrameworkCore.Tests.csproj
index 77b1448ded..137dba20f4 100644
--- a/framework/test/Volo.Abp.EntityFrameworkCore.Tests/Volo.Abp.EntityFrameworkCore.Tests.csproj
+++ b/framework/test/Volo.Abp.EntityFrameworkCore.Tests/Volo.Abp.EntityFrameworkCore.Tests.csproj
@@ -9,6 +9,7 @@
 
   <ItemGroup>
     <ProjectReference Include="..\..\src\Volo.Abp.Autofac\Volo.Abp.Autofac.csproj" />
+    <ProjectReference Include="..\..\src\Volo.Abp.EntityFrameworkCore.MySQL\Volo.Abp.EntityFrameworkCore.MySQL.csproj" />
     <ProjectReference Include="..\..\src\Volo.Abp.EntityFrameworkCore.Sqlite\Volo.Abp.EntityFrameworkCore.Sqlite.csproj" />
     <ProjectReference Include="..\AbpTestBase\AbpTestBase.csproj" />
     <ProjectReference Include="..\Volo.Abp.EntityFrameworkCore.Tests.SecondContext\Volo.Abp.EntityFrameworkCore.Tests.SecondContext.csproj" />
diff --git a/framework/test/Volo.Abp.EntityFrameworkCore.Tests/Volo/Abp/EntityFrameworkCore/MySQL/MySQLGuidArrayTypeMappingSourcePlugin_Tests.cs b/framework/test/Volo.Abp.EntityFrameworkCore.Tests/Volo/Abp/EntityFrameworkCore/MySQL/MySQLGuidArrayTypeMappingSourcePlugin_Tests.cs
new file mode 100644
index 0000000000..2114e87b0e
--- /dev/null
+++ b/framework/test/Volo.Abp.EntityFrameworkCore.Tests/Volo/Abp/EntityFrameworkCore/MySQL/MySQLGuidArrayTypeMappingSourcePlugin_Tests.cs
@@ -0,0 +1,58 @@
+using System;
+using Microsoft.EntityFrameworkCore;
+using Microsoft.EntityFrameworkCore.Infrastructure;
+using Microsoft.EntityFrameworkCore.Storage;
+using Microsoft.Extensions.DependencyInjection;
+using Shouldly;
+using Volo.Abp.EntityFrameworkCore.DependencyInjection;
+using Xunit;
+
+namespace Volo.Abp.EntityFrameworkCore.MySQL;
+
+public class MySQLGuidArrayTypeMappingSourcePlugin_Tests
+{
+    /* Runs without a MySQL server: type mapping lookup is metadata-only, no
+     * connection is opened. When upgrading the provider, verify its native
+     * Guid[] mapping without the plugin registered; once the provider handles
+     * Guid[] itself, remove MySQLGuidArrayTypeMappingSourcePlugin together
+     * with this test. */
+    [Fact]
+    public void UseMySQL_Should_Map_Guid_Array_Parameter_To_A_Collection_Mapping()
+    {
+        var services = new ServiceCollection();
+        services.AddLogging();
+
+        var configurationContext = new AbpDbContextConfigurationContext(
+            "Server=localhost;Database=_;Uid=_;Pwd=_;",
+            services.BuildServiceProvider(),
+            null,
+            null);
+        configurationContext.UseMySQL();
+
+        using var dbContext = new PluginTestDbContext(configurationContext.DbContextOptions.Options);
+        var typeMappingSource = dbContext.GetService<IRelationalTypeMappingSource>();
+        var elementMapping = typeMappingSource.FindMapping(typeof(Guid))!;
+
+        var mapping = typeMappingSource.FindMapping(typeof(Guid[]), dbContext.Model, elementMapping);
+
+        mapping.ShouldNotBeNull();
+        mapping.ClrType.ShouldBe(typeof(Guid[]));
+        mapping.StoreType.ShouldBe("longtext");
+        mapping.ElementTypeMapping.ShouldBe(elementMapping);
+    }
+
+    private class PluginTestDbContext : DbContext
+    {
+        public PluginTestDbContext(DbContextOptions options)
+            : base(options)
+        {
+        }
+
+        public DbSet<PluginTestEntity> Entities => Set<PluginTestEntity>();
+    }
+
+    private class PluginTestEntity
+    {
+        public Guid Id { get; set; }
+    }
+}